| 胃溃疡及胃炎患者幽门螺杆菌耐药性分析 |
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| 引用本文： | 黄宏思,黄衍强,黄赞松,周喜汉,岑朝,俞文强.胃溃疡及胃炎患者幽门螺杆菌耐药性分析[J].中国公共卫生,2010,26(1). |
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| 作者姓名： | 黄宏思 黄衍强 黄赞松 周喜汉 岑朝 俞文强 |
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| 作者单位： | 1. 右江民族医学院微生物学教研室,广西,百色,533000
2. 右江民族医学院附属医院 |
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| 基金项目： | 广西自然科学基金，广西教育厅科研项目 |
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| 摘 要： | 目的 了解胃溃疡及胃炎患者幽门螺杆菌(Helicobacterpylori,Hp)对甲硝唑等抗生素的耐药情况.方法 采集右江民族医学院附属医院近3年确诊为Hp感染患者的胃窦部黏膜样本进行Hp分离培养和鉴定,经鉴定后选择374株Hp菌株,采用纸片扩散法测定其对甲硝唑、阿莫西林、克拉霉素等抗生素的敏感性.结果 Hp对甲硝唑、阿莫西林、克拉霉素的耐药率从2006年的68.6%,10.2%,15.3%分别上升到2008年的91.7%,21.2%,28.8%;部分Hp同时对多种抗生素耐药,同时对甲硝唑、克拉霉素和阿莫西林耐药的有14株,耐药率为3.74%.结论 胃溃疡及胃炎患者Hp对甲硝唑、阿莫西林、克拉霉素均有一定耐药性,有必要使用其他抗生素替代.
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| 关 键 词： | 幽门螺杆菌 抗生素 耐药 |
Drug resistance of Helicobacter pylori to antibiotic among gastric ulcer and gastritis patients in west Guangxi |
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| HUANG Hong-si,HUANG Yan-qiang,HUANG Zan-song,et al..Drug resistance of Helicobacter pylori to antibiotic among gastric ulcer and gastritis patients in west Guangxi[J].Chinese Journal of Public Health,2010,26(1). |
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| Authors: | HUANG Hong-si HUANG Yan-qiang HUANG Zan-song |
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| Institution: | HUANG Hong-si,HUANG Yan-qiang,HUANG Zan-song,et al.Department of Microbiology,Youjiang Medical College for Nationalities(Baise 533000,China) |
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| Abstract: | Objective To investigate the antibiotic resistance of Helicobacter pylori ( Hp) to metronidazole,amoxicillin,clarithromycin among gastric ulcer and gastritis patients in west Guangxi.Methods Gastric mucosa biopsy specimens were taken from the patients diagnosed from 2006 through 2008.Three hundred seventy-four strains were diagnosed.The resistance to metronidazole,amoxicillin and clarithromycin of the strains were determined with K-B diffusion test.Results The resistance rates were 68.6%,10.2%,15.3% for met... |
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| Keywords: | Helicobacter pylori antibiotic drug resistance |
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