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Molecular diagnosis of ureaplasma urealyticum septic arthritis in a patient with hypogammaglobulinemia |
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| Authors: | Albert H. Lee Thaila Ramanujam Paul Ware Paul H. Edelstein John J. Brooks Bruce Freundlich H. Ralph Schumacher Robert B. Zurier David B. Weiner William V. Williams |
| Abstract: | Objective. We report a hypogammaglobulinemic patient with a destructive oligoarticular arthritis, whose synovial fluid cultures were repeatedly sterile. Methods and Results. We identified a Ureaplasma urealyticum infection in his affected joints, using a polymerase chain reaction (PCR) assay. Conclusion. The PCR technique promises to be extremely valuable in the rapid and specific diagnosis of infectious arthritis. |
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