Schisandra sphenanthera extract (Wuzhi Tablet) protects against chronic-binge and acute alcohol-induced liver injury by regulating the NRF2-ARE pathway in mice |
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| Affiliation: | 1. School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China;2. Department of Pharmacy, School of Medicine, Shenzhen University, Guangdong 518060, China;3. Shenzhen Bao׳an Maternal and Child Health Hospital, Guangdong 518133, China |
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| Keywords: | ALD" },{" #name" :" keyword" ," $" :{" id" :" key0010" }," $$" :[{" #name" :" text" ," _" :" alcoholic liver disease ALT" },{" #name" :" keyword" ," $" :{" id" :" key0020" }," $$" :[{" #name" :" text" ," _" :" alanine aminotransferase AST" },{" #name" :" keyword" ," $" :{" id" :" key0030" }," $$" :[{" #name" :" text" ," _" :" aspartate aminotransferase ARE" },{" #name" :" keyword" ," $" :{" id" :" key0040" }," $$" :[{" #name" :" text" ," _" :" antioxidant response element CYP2E1" },{" #name" :" keyword" ," $" :{" id" :" key0050" }," $$" :[{" #name" :" text" ," _" :" cytochrome P450 2E1 enzyme EtOH" },{" #name" :" keyword" ," $" :{" id" :" key0060" }," $$" :[{" #name" :" text" ," _" :" ethanol GCLC" },{" #name" :" keyword" ," $" :{" id" :" key0070" }," $$" :[{" #name" :" text" ," _" :" glutamate–cysteine ligase catalytic subunit GCLM" },{" #name" :" keyword" ," $" :{" id" :" key0080" }," $$" :[{" #name" :" text" ," _" :" glutamate–cysteine ligase modifier subunit GSH" },{" #name" :" keyword" ," $" :{" id" :" key0090" }," $$" :[{" #name" :" text" ," _" :" glutathione H&E" },{" #name" :" keyword" ," $" :{" id" :" key0100" }," $$" :[{" #name" :" text" ," _" :" hematoxylin and eosin HO-1" },{" #name" :" keyword" ," $" :{" id" :" key0110" }," $$" :[{" #name" :" text" ," _" :" heme oxygenase-1 NRF2" },{" #name" :" keyword" ," $" :{" id" :" key0120" }," $$" :[{" #name" :" text" ," _" :" nuclear factor erythroid 2-related factor 2 SOD" },{" #name" :" keyword" ," $" :{" id" :" key0130" }," $$" :[{" #name" :" text" ," _" :" superoxide dismutase WZ" },{" #name" :" keyword" ," $" :{" id" :" key0140" }," $$" :[{" #name" :" text" ," _" :" Wuzhi Tablet. Alcoholic liver injury Wuzhi Tablet NRF2-ARE Oxidative stress |
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