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Metastatic renal cell carcinoma presenting as a gallbladder polyp
Institution:1. Department of Obstetrics and Gynecology, Tohoku University School of Medicine, 1-1, Seiryo-machi, Sendai 980-8574, Japan;2. Department of Pathology, Tohoku University School of Medicine, 1-1, Seiryo-machi, Sendai 980-8574, Japan;1. University of Rochester School of Medicine and Dentistry, Rochester, NY, United States;2. University of Ulster, Coleraine, Northern Ireland, UK;3. National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, United States;4. Ministry of Health, Republic of Seychelles
Abstract:Clear cell renal cell carcinoma accounts for approximately 3% of all adult malignancies and 85% of all primary renal malignancies. Clear cell renal cell carcinoma (ccRCC) metastasis to the gallbladder is extremely rare and often presents as a metachronous metastasis following several years of tumour free disease. We report a case of a 78-year-old female with metastatic ccRCC to the gallbladder. During follow-up ultrasound imaging, a polypoid gallbladder mass was discovered incidentally. The previous medical history is significant for total nephrectomy for left-sided ccRCC 6 years ago. A new suspicious intraluminal polypoid gallbladder mass in a patient with a history significant for clear cell renal cell carcinoma should alert the physician to consider metastatic clear cell renal cell carcinoma.
Keywords:clear cell renal cell carcinoma  gallbladder  metastasis
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