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Salivary Gland Tumors: Current Concepts and Controversies
Affiliation:1. Department of Cranio-Maxillofacial Surgery, University Hospital Münster, Münster, Germany;2. Bone Tumour Reference Centre and DÖSAK Registry, Institute of Pathology, University Hospital Basel, University of Basel, Basel, Switzerland;3. Gerhard-Domagk-Institute of Pathology, University Hospital Münster, Münster, Germany;1. Department of Oral Surgery, Odontology, Timone Hospital, 13385 Marseille, France;2. Department of Stomatology, Oral & Maxillofacial surgery, Conception Hospital, 13005 Marseille, France;3. Department of Pathological Anatomy & Cytology, University Cancer Institute Toulouse Oncopole, 31059 Toulouse, France;4. Department of Plastic & Maxillofacial Surgery, Pierre-Paul Riquet Hospital, 31059 Toulouse, France;5. UMR 7268 ADES, Faculty of Medicine, Aix-Marseille University/EFS/CNRS, 13344 Marseille, France;1. Department Melanoma, Soft Tissues, Musculoskeletal and Head & Neck, Italian National Cancer Institute – IRCCS Pascale Foundation, Naples, Italy;2. Department of Otorhinolaryngology, University of Brescia, Italy;3. Department of Pathology and Cytopathology, Italian National Cancer Institute – IRCCS Pascale Foundation, Naples, Italy;4. Department of Radiology, University of Brescia, Italy;5. Particle Therapy Cancer Research Institute, CNAO Foundation, Milan, Italy;6. Evaluative Epidemiology Unit, Fondazione IRCCS “Istituto Nazionale dei Tumori”, Milan, Italy;7. First Department of Medicine, Laiko General Hospital, Athens, Greece;1. Department of Oral and Maxillofacial Surgery, Aristotle University of Thessaloniki, “G. Papanikolaou” General Hospital, Thessaloniki, Greece;2. Department of Oral and Maxillofacial Surgery, University of Rochester, Rochester, New York, USA;1. Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan;2. Department of Medical Research, Chung Shan Medical University Hospital, Taichung, Taiwan;3. Department of Dentistry, Chung Shan Medical University Hospital, Taichung, Taiwan;4. School of Dentistry, Chung Shan Medical University, Taichung, Taiwan
Abstract:This current review focuses on current concepts and controversies for select key salivary gland epithelial neoplasms. Rather than the traditional organization of benign and malignant tumors, this review is structured around select key topics: biphasic tumors, mammary analogue secretory carcinoma, and the controversy surrounding polymorphous low-grade adenocarcinoma and cribriform adenocarcinoma of (minor) salivary gland origin.
Keywords:Salivary gland  Translocations  Molecular  Correlative  Neoplasia  Classification
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