Regulation of immune-related diseases by multiple factors of chromatin,exosomes, microparticles,vaccines, oxidative stress,dormancy, protein quality control,inflammation and microenvironment: a meeting report of 2017 International Workshop of the Chinese Academy of Medical Sciences (CAMS) Initiative for Innovative Medicine on Tumor Immunology |
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| Affiliation: | 1. State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China;2. National Key Laboratory of Medical Molecular Biology, Department of Immunology, Institute of Basic Medical Sciences and Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100005, China;3. Department of Surgery, University of Michigan School of Medicine, Ann Arbor, MI 48109, USA; The University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA; Graduate Programs in Immunology and Tumor Biology, University of Michigan, Ann Arbor, MI 48109, USA;4. Department of Pathology and Molecular Medicine, McMaster Immunology Research Centre, McMaster University, Hamilton, Ontario L8N 3Z5, Canada;5. Laboratory for Cellular Biomechanics and Regenerative Medicine, Department of Biomedical Engineering, School of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China; Department of Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA;6. Sino-British Research Centre for Molecular Oncology, National Center for International Research in Cell and Gene Therapy, Zhengzhou University, Zhengzhou, 450001, China; School of Basic Medical Sciences, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, 450001, China; Center for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London EC1M 6BQ, UK;7. Diabetes Research Center of Chinese Academy of Medical Sciences, Beijing 100050, China;8. Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China;9. Department of Biochemistry & Molecular Biology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, 430030, China; Clinical Immunology Center, Chinese Academy of Medical Sciences, Beijing, 100050, China |
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| Abstract: | Immune cells play key roles in cancer and chronic inflammatory disease. A better understanding of the mechanisms and risks will help develop novel target therapies. At the 2017 International Workshop of the Chinese Academy of Medical Sciences (CAMS) Initiative for Innovative Medicine on Tumor Immunology held in Beijing, China, on May 12, 2017, a number of speakers reported new findings and ongoing studies on immune-related diseases such as cancer, fibrotic disease, diabetes, and others. A considerably insightful overview was provided on cancer immunity, tumor microenvironments, and new immunotherapy for cancer. In addition, chronic inflammatory diseases were discussed. These findings may offer new insights into targeted immunotherapy. |
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| Keywords: | Tumor Immunology Chromatin Exosomes Microparticles Vaccines Oxidative stress Dormancy Protein Quality Control Inflammation |
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