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A 15-year experience of two hundred and twenty five consecutive right hepatectomies
Affiliation:1. Division of General Surgery and Liver Transplantation, S. Camillo Hospital, Rome, Lazio, Italy;2. Hepatology and Infectious Diseases Unit, National Institute for Infectious Diseases “L. Spallanzani”, Rome, Italy;3. Anesthesiology and Intensive Care Unit, National Institute for Infectious Disease “L. Spallanzani”, Rome, Italy;4. Diagnostic Imaging Department, National Institute for Infectious Diseases “Lazzaro Spallanzani”, Rome, Italy;5. Department of Radiology, Azienda Ospedaliera San Camillo Forlanini, Rome, Italy;6. Department of Oncology—Ospedale Civile di Pescara, Pescara, Italy
Abstract:BackgroundIn case of liver tumor, surgical resection is the therapeutic gold standard to increase patient survival. Among liver resections, right hepatectomy (RH) is defined as a major hepatectomy. The first aim of this study was to analyze the overall morbidity and mortality of patients undergoing RH, the second aim was to assess changes in both patients characteristic and surgical parameters and mortality rates in a single center institution.MaterialsFrom 2001 to December 2015, 225 RH were performed in our center. We analyzed two time period: 2001–2007 and 2008–2015.ResultsNinety days post operative mortality was observed in 9 cases (4%) for the overall cohort. We observed a difference between the two groups in the use of Pringle Maneuver (p < 0,001). This result is consistent in each major surgical indication: HCC (p = 0,001), CLM (p = 0,015) and BT (p = 0,015). The estimated blood losses improved (p = 0,028), particularly for the HCC cases (p = 0,024). No difference was observed in terms of number of transfusions received between the two groups. Reduced length of stay was observed in the second group (p < 0,001), more markedly for CLM cases (p = 0,001).ConclusionTo further improve the outcomes of RH, it is important to performed this major hepatectomy in hepatobiliary centers with an overall liver resection experience of at least few hundred cases.
Keywords:Right hepatectomy  Liver surgery  Colorectal metastases  Hepatocellular carcinoma  Major liver resection
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