首页 | 本学科首页   官方微博 | 高级检索  
检索        

气相色谱-质谱和化学计量学解析法分析药对麻黄-桂枝挥发油成分
引用本文:李晓如,梁逸曾,李晓宁.气相色谱-质谱和化学计量学解析法分析药对麻黄-桂枝挥发油成分[J].药学学报,2007,42(2):187-191.
作者姓名:李晓如  梁逸曾  李晓宁
作者单位:中南大学,化学化工学院,湖南,长沙,410083
基金项目:国家自然科学基金;教育部高等学校科技创新工程项目
摘    要:利用气相色谱-质谱对药对麻黄-桂枝及单味药麻黄和桂枝的挥发油成分进行检测,通过化学计量学解析法对产生的二维色谱-质谱数据进行解析,得到各组分的纯色谱和质谱,根据其保留时间和质谱,在质谱库中进行相似检索,实现对组分的定性,再用总体积积分法进行定量。麻黄-桂枝、麻黄和桂枝挥发油分别定性了97,72和68个色谱峰,占总含量的89.76%,90.08%和91.62%。药对挥发油成分的数目大致为麻黄和桂枝挥发油成分的加和,但相对含量有变化。

关 键 词:药对麻黄-桂枝  挥发油  气相色谱-质谱  化学计量学解析法
文章编号:0513-4870(2007)02-0187-05
收稿时间:2006-05-15
修稿时间:2006-05-15

Analysis of essential oil in Herba Ephedrae-Ramulus Cinnamomi by GC-MS and chemometric resolution method
LI Xiao-ru,LIANG Yi-zeng,LI Xiao-ning.Analysis of essential oil in Herba Ephedrae-Ramulus Cinnamomi by GC-MS and chemometric resolution method[J].Acta Pharmaceutica Sinica,2007,42(2):187-191.
Authors:LI Xiao-ru  LIANG Yi-zeng  LI Xiao-ning
Institution:College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China
Abstract:Gas chromatography/mass spectrometry,chemometric resolution method(CRM)and overall volume integration method were used to analyze the essential components of herbal pair Herba Ephedrae-Ramulus Cinnamomi(HP HE-RC)and compare it with that of single herbs HE and RC.72,68,and 97 essential components in essential oil of HE,RC,and HP HE-RC were determined,accounting for 90.08%,91.62%,and 89.76% of total contents of essential oil of HE,RC,and HP HE-RC,respectively.The numbers of essential components of HP HE-RC are almost the summation of that of two single herbs,but some relative contents of them are changed.Some new components,such as 1,6-dimethylhepta-1,3,5-triene,tetracyclo4.2.1.1(2,5).0(9,10)]deca-3,7-diene,globulol,(E,E)-6,10,14-trimethyl-5,9,13-pentadecatrien-2-one,etc.have been found in HP HE-RC because of chemical reactions and physical changes during the course of decocation.
Keywords:herbal pair resolution method Herba Ephedrae-Ramulus Cinnamomi  essential oil  GC-MS  chemometric
本文献已被 CNKI 维普 万方数据 等数据库收录!
点击此处可从《药学学报》浏览原始摘要信息
点击此处可从《药学学报》下载免费的PDF全文
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号