哥兰叶化学成分的研究

为研究哥兰叶(Celastrus gemmatus Loes.)中的化学成分，用Diaion HP-20，Toyopearl HW-40，silica gel等柱色谱方法，从其70%含水丙酮提取物中分离得到化合物，并根据理化性质和波谱数据鉴定其结构。共得到9个化合物，分别为左旋马尾松树脂醇-3a-O-β-D-吡喃葡糖苷(1)，ambrosidine(2)，异落叶松脂素-9-O-β-D-吡喃葡糖苷(3)，山柰酚-3-O-β-D-吡喃葡糖苷(紫云英苷)(4)，山柰酚-3-O-α-L-吡喃鼠李糖基-(1→6)-β-D-吡喃葡糖苷(5)，山柰酚-3-O-α-L-吡喃鼠李糖基-(1→2)-β-D-吡喃葡糖苷(6)，芹菜素-7-O-β-D-葡糖醛酸苷(7)，芹菜素-7-O-β-D-吡喃葡糖醛酸甲酯(8)，D-山梨醇(9)。化合物1为新化合物，其余化合物为首次从该属植物中分离得到。本文为首次报道该属植物中的木脂素类化合物。

Chemical constituents from leaves of Celastrus gemmatus Loes.

To study the chemical constituents from the leaves of Celastrus gemmatus Loes., chromatographic methods were used to isolate and purify the chemical constituents, their structures were elucidated by the physiochemical characteristics and spectral data. Nine compounds were obtained and identified as (-)-massoniresinol 3a-O-beta-D-glucopyranoside (1), ambrosidine (2), isolariciresinol 9-O-beta-D-glucopyranoside (3), kaempferol 3-O-beta-D-glucopyranoside (astragalin) (4), kaempferol 3-O-rutinoside (5), kaempferol 3-O-neohesperidoside (6), apigenin 7-O-beta-D-glucuronide (7), apigenin 7-O-beta-D-glucuronide methyl ester (8) and D-sorbitol (9). Compound 1 is a new compound, the others are isolated from this genus for the first time, and this is the first time to report lignan compounds from genus Celastrus.