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浅裂鳞毛蕨根茎中的二氢黄酮苷类化学成分
引用本文:冯卫生,曹新伟,匡海学,郑晓珂. 浅裂鳞毛蕨根茎中的二氢黄酮苷类化学成分[J]. 药学学报, 2007, 42(8): 867-871
作者姓名:冯卫生  曹新伟  匡海学  郑晓珂
作者单位:1. 河南中医学院,河南,郑州,450008
2. 黑龙江中医药大学,黑龙江,哈尔滨,150040
基金项目:教育部科学技术研究重点项目
摘    要:为研究浅裂鳞毛蕨根茎中的化学成分,用Sephadex LH-20,silica gel等柱色谱方法从其水提物中分离得到化合物,并根据理化性质和波谱数据鉴定其结构。分离得到9个化合物,分别为浅裂鳞毛蕨素A(1),浅裂鳞毛蕨素B(2),浅裂鳞毛蕨素C(3),浅裂鳞毛蕨素D(4),东方荚果蕨酯A(5),东方荚果蕨酯C(6),熊果苷(7),3-甲氧基-4-羟基苯基-1-O-β-D-葡糖苷(8)和3,4-二甲基苯基-1-O-β-D-葡糖苷(9)。其中化合物1~4为新化合物,其余均为首次从本植物中分得。

关 键 词:浅裂鳞毛蕨  二氢黄酮苷  结构鉴定
文章编号:0513-4870(2007)08-0867-05
收稿时间:2007-01-22
修稿时间:2007-01-22

Flavanone O-glycosides from the rhizomes of Dryopteris sublaeta
FENG Wei-sheng,CAO Xin-wei,KUANG Hai-xue,ZHENG Xiao-ke. Flavanone O-glycosides from the rhizomes of Dryopteris sublaeta[J]. Acta pharmaceutica Sinica, 2007, 42(8): 867-871
Authors:FENG Wei-sheng  CAO Xin-wei  KUANG Hai-xue  ZHENG Xiao-ke
Affiliation:Henan College of Traditional Chinese Medicine, Zhengzhou 450008, China;Henan College of Traditional Chinese Medicine, Zhengzhou 450008, China;Heilongjiang University of Traditional Chinese Medicine, Harbin 150040, China;Henan College of Traditional Chinese Medicine, Zhengzhou 450008, China
Abstract:The aim of this study was to look for the chemical constituents from the rhizomes of Dryopteris sublaeta. The fresh plant was extracted twice with boiling water, the extract was concentrated to small volume under reduced pressure at 50 degrees C. The concentrated material was partitioned with ether, ethyl acetate and n-butanol. The fraction of ethyl acetate was repeatedly chromatographied over silica gel and Sephadex LH-20 columns. Structures of pure compounds were established on the basis of their physiochemical and spectral data. Nine compounds were obtained and identified as sublaetentin A (1), sublaetentin B (2), sublaetentin C (3), sublaetentin D (4), matteuorienate A (5), matteuorienate C (6), arbutin (7), 3-methoxy-4-hydroxyphenyl-1-O-beta-D-glucopyranoside (8) and 3,4-dimethoxyphenyl-1-O-beta-D-glucopyranoside (9). Compounds 1 - 4 are new compounds, the others were isolated from this plant for the first time.
Keywords:Dryopteris sublaeta  flavanone O-glycosides  structure identification
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