犬颅脑爆震伤战地早期救治的疗效观察

目的：观察野战环境战地早期救治对颅脑爆震伤实验犬的救治效果。方法：杂种雄性犬30只,随机分为：对照组（n=6）,外伤组（n=12）及治疗组（n=12）,制作成颅脑爆震伤模型,治疗组运用大剂量青霉素、甘露醇等进行治疗,观察每一组呼吸、心率、血压、颅内压、生存时间的变化。结果：动物伤后两模型组均出现呼吸、心率减慢、血压降低、颅内压升高,与伤前比较有非常显著差异（P〈0.01）,经药物治疗后治疗组与外伤组有显著差异（P〈0.05）;生存时间为治疗组（138.6±8.0h）,外伤组（96.5±3.0h）,两组有非常显著差异（P〈0.01）。结论：早期积极有效的治疗能改善颅脑爆震伤实验犬呼吸、心率、血压、颅内压、生存时间等生命指标,提高颅脑爆震伤犬的救治效果。

Early treatment of dogs with craniocerebral explosive injury under the field situation

Objective： To observe the effects of early treatment on dogs with craniocerebral explosive injury under the field situation. Methods： Thirty mongrel male dogs were randomly divided into control group （ n = 6） , injury group （ n = 12） and treatment group （ n = 12） . The injury group and treatment group were established into models of craniocerebral explosive injury. Respiratory frequency（ R） ,heart rate（ HR） ,blood pressure（ BP） , intracranial pressure （ ICP） ,and the survival time were observed in each group. Results： Compared with pretherapy,the index levels of R,HR,BP in both model groups were decreased significantly after cerebral explosive injury （ P 0. 05） ,however,ICP were increased （ P 0. 01） . The index levels were relieved significantly in the treatment group as compared with that of the injury group （ P 0. 05） . The survival time of the treatment group （ 138. 6 ±8. 0 ） h was significantly longer than that of injury group （ 96. 5 ± 3. 0 ） h （ P 0. 01） . Conclusion： Early proper treatment for craniocerebral explosive injury in dogs can relieve the index levels of R,HR,BP,ICP and prolong the survival time under the field situation.