卡前列素氨丁三醇预防宫缩乏力性产后出血的临床研究

目的 观察卡前列素氨丁三醇联合缩宫素预防宫缩乏力性产后出血的临床效果.方法 选择120例有宫缩乏力性产后出血高危因素的产妇,随机分为试验组和对照组,比较两组第三产程时间,产后2 h及24 h出血量及产后出血发生率.试验组：胎儿娩出后宫体注射卡前列素氨丁三醇250 μg同时静滴缩宫素20 U.对照组：胎儿娩出后舌下含服米索前列醇200 μg同时静滴缩宫素20 U.结果 试验组比对照组产后2 h及24 h平均出血量减少,第三产程时间缩短,产后出血率降低,差异均有显著性.结论 卡前列素氨丁三醇比米索前列醇更有效预防产后出血,且具有安全,高效,迅速,方便的特点.

Clinical study on preventing atonic postpartum hemorrhage with hemabate

Objective To investigate the clinical obsenation of the effiect of hemorrhage oxyt combined with oein in preventing atonic postpartum hemorrhage. Methods 120 high risk pregnant women were divided randomly into grops experiental grunp, （ groupl ） and control group（ group 2 ） . The groupl was given Hemabate 250 μg into uterine muscle after delivery of the fetus,and oxytocin 20 U into vein. The group 2 was given misoprostol 200 μg by sublingua/after delivery of the fetus ,and oxytoein 20U into vein . The amount of bleeding within 2 hours and 24 hours after deliver7 for the two group was measured. Results The amount of bleeding within 2 and 24 hours after delivery in group I were both much less than those in group 2. The length of third - trimester of group 1 was shorter titan that of group 2 . The incidence of postpartum hemorrhage in group lwas lower than that in group 2. Conclusion Hemabate is more effective in reduction and prevention of atonic postpartum hemorrhage,and it is safe, efficient, quick and convenient.