血清甘油三酯和白蛋白水平与急性胰腺炎严重程度的相关性研究

目的探讨血清甘油三酯和白蛋白水平对急性胰腺炎严重程度的评估意义。方法回顾性分析在笔者所在医院住院的333例急性胰腺炎患者，其中轻症急性胰腺炎251例，重症急性胰腺炎82例；并选同期住院的非急性胰腺炎患者237例作为对照组．于24h内分别测定血清甘油三酯（TG）、胆固醇（TC），高密度脂蛋白（HDL-C）、低密度脂蛋白（LDL—C）和白蛋白（ALB）。结果急性胰腺炎组TG水平高于对照组（P〈0．05），重症急性胰腺炎组TG水平明显高于轻症急性胰腺炎组（P〈0．01）。而TC、HDL—C和LDL—C在三组间差异无统计学意义（P〉0．05）；血清TG水平与胰腺炎严重程度呈正相关（r=0．300，P=0．000）。急性胰腺炎组ALB水平低于对照组（P〈0．05），重症急性胰腺炎组ALB水平明显低于轻症急性胰腺炎组（P〈0．01）；ALB水平与胰腺炎严重程度呈负相关（r=-0．460，P=0．000）。结论血清甘油三酯和白蛋白水平可以作为预测评估急性胰腺炎严重程度的指标之一。

Research about the relation between the level of serum triglyceride and albumin and the severity of acute pancreatitis

Objective To investigate the level of serum triglyceride and albumin to the assessment - significance of the severity of acute pancreatitis （AP） , Methods A retrospective analysis of hospitalized patients with AP were 333 cases, of which 251 cases of mild acute pancreatitis （MAP） , 82 cases with severe acute pancreatitis （SAP） ;and selected the same period in hospitalized patients with 237 cases of uon - AP as a control group, in were detected within 24 h of serum triglyceride （TG） and cholesterol （TC）, high density lipoprotein （HDL- C）, low density lipoproteiu （LDL- C） and albumin （ALB）. Results AP group higher TG levels （ P 〈0.05 ）, SAP group TG levels were significantly higher than the MAPgroup （P 〈0. 01 ）. The TC, HDL - C and LDL - C among the three groups had no statistically significant difference （P 〉 0. 05 ） ; serum TG levels and pancreatitis severity were positively correlated （ r = 0. 300, P = 0. 000 ）. AP Group ALB were lower than the control group （P 〈 0. 05 ）, SAP group ALB levels were significantly lower than MAP group （P 〈 0. 01 ） ;ALB levels and pancreatitis severity were negatively correlated （ r = -0. 460, P = 0. 000 ）. Conclusion Serum triglycerides and albumin levels can be assessed as a predictor of the severity of acute pancreatitis.