| 微粒子酶免疫化学发光法和ELISA定量检测CCP抗体的临床应用评价 |
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| 引用本文： | 刘永林,陈益民,张丽,张蕾,张燕,骆丰,陈婷婷. 微粒子酶免疫化学发光法和ELISA定量检测CCP抗体的临床应用评价[J]. 放射免疫学杂志, 2011, 24(2): 180-182 |
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| 作者姓名： | 刘永林 陈益民 张丽 张蕾 张燕 骆丰 陈婷婷 |
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| 作者单位： | 浙江省中医院检验科,310006 |
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| 摘 要： | 目的:应用化学发光法、酶联免疫吸附试验(ELISA)定量检测类风湿性关节炎(RA)患者抗环瓜氨酸多肽(CCP)抗体的含量,探讨CCP抗体在RA早期诊断和治疗中的作用.方法:选取69例RA、30例强直性脊柱炎(AS)、33例干燥综合征(SS)患者、61例健康体检人群,分别用化学发光、ELISA检测其血清CCP抗体的含量....
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| 关 键 词： | 类风湿性关节炎 抗环瓜氨酸多肽抗体 化学发光法 酶联免疫吸附试验 |
Diagnostic Value of Anti-Cyclic Citrulinated Peptide Antibody by Using MEIA and ELISA in Patients with Rheumatoid Arthritis |
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| Liu Yong-lin,Chen Yi-min,Zhang Li,et al.. Diagnostic Value of Anti-Cyclic Citrulinated Peptide Antibody by Using MEIA and ELISA in Patients with Rheumatoid Arthritis[J]. Journal of Radioimmanology, 2011, 24(2): 180-182 |
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| Authors: | Liu Yong-lin Chen Yi-min Zhang Li et al. |
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| Affiliation: | Liu Yong-lin,Chen Yi-min,Zhang Li,et al.Department of Laboratory,Zhijiang Provence Traditional Chinese Medicine Hospital,Hangzhou(310006),China |
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| Abstract: | Objective To evaluate the sensitivity and specificity of anti-cyclic citrullinated peptide antibody(anti-CCP) in patients with rheumatoid arthritis(RA).Methods Anti-CCP antibodies were examined by using MEIA and ELISA from 69 RA,30 Ankylosingspondylitis(AS),33 Siccasyndrome(SS) and 61 normal donors sera.Results Among 69 patients with RA,The sensitivity and specificity of anti-CCP were(69.56%,68.11%),(96.77%,97.26%) by MEIA and ELISA in RA respectively.The data showed that there was a significant difference ... |
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| Keywords: | rheumatoid arthritis(RA) anti-cyclic citrullinated peptide antibody(anti-CCP) MEIA ELISA |
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