四类重点人群HIV、梅毒、肝炎感染状况调查

目的了解中小工业城市重点人群HIV、梅毒和肝炎的感染现状。方法现场调查采用哨点监测的方法，血清检测应用ELISA法，检测了256名有偿供血者、266名性病门诊患者、271名孕妇、228名吸毒者的HIV抗体、梅毒抗体、抗-HCV和乙肝HBsAg。结果吸毒者检出1例HIV抗体阳性，阳性检出率为0．43％，吸毒者丙型肝炎的感染率为83.87％，与有偿供血者（5.86％）、性病门诊患者（2．26％）和孕妇（1．11％）相比较均有统计学意义，有偿供血者丙型肝炎感染率与除吸毒人群外的其他两类人群比较也有统计学意义。经多因素logistic回归分析发现性病门诊患者梅毒感染率与性别、年龄、婚外性伴数呈正相关。结论性病门诊患者和吸毒人群梅毒感染率、吸毒人群和有偿供血者丙型肝炎感染率较高，性病门诊患者和吸毒人群存在感染HIV／性病的危险因素。应加强上述重点人群的监测和管理，防止艾滋病等疾病的流行。

Survey on HIV, syphilis and hepatitis infection among four types of important groups

Objective To understand the prevalence of HIV, HBV, HCV and syphilis infection among four types of important groups. Methods Serum samples of 256 paid blood-donors, 228 drug users, 266 STD clinic out-patients and 271 pregnant women were detected with ELISA method for anti-HIV, anti-HCV, HBsAg and syphilis antibody. Results The HIV prevalence rate among drug users was 0.43%. The hepatitis C prevalence rate among drug users was 83.87%, siginificantly higher than that of blood-donors (5.86%), STD clinic out-patients (2.26%) and pregnant women (1.11%). The hepatitis C prevalence rate among blood-donors was also significantily higer than that of the other two groups except for drug users. By logistic regression analysis, we found that the syphilis infection rate of STD clinic out-patients related to sex, age and number of illicit sex partners. Conclusions The prevalence rate of syphilis among STD clinic out-patients and drug users are very high and so is the prevalence rate of hepatitis C among drug users and blood-donors. The evidence indicates AIDS is likely to spread among drug users in Maanshan city, so the effective interventions must be taken to prevent the transmission of HIV/STD and hepatitis.