临床常见革兰阳性球菌的耐药性分析

目的了解临床常见革兰阳性球菌的耐药性,指导临床合理使用抗菌药物。方法对2009～2011年临床分离常见革兰阳性球菌进行药敏试验,并用WHONET 5.4软件进行数据分析。结果金黄色葡萄球菌、表皮葡萄球菌、溶血葡萄球菌、肺炎链球菌、粪肠球菌的分离率分别为36.95%、23.56%、17.14%、12.18%、10.17%;耐甲氧西林金黄色葡萄球菌(MRSA)为45.65%,耐苯唑西林表皮葡萄球菌、耐甲氧西林凝固酶阴性葡萄球菌(MRC-NS)分别为78.13%、64.77%,青霉素不敏感肺炎链球菌(PNSP)为51.65%,常见革兰阳性球菌未发现耐万古霉素。结论临床常见革兰阳性球菌的感染已经变得非常普遍,MRSA、MRCNS、PNSP和粪肠球菌对于常用抗菌药物出现了较高的耐药率,依据药敏试验的结果合理选用抗菌药物非常必要。

The drug fast analysis of the common clinical Gram Positive Coccus

Objective To understand the drug fast of the common clinical Gram Positive Coccus and to instruct the proper clinical application of antibacterial.Methods Gram Positive Coccus separated from 2009 to 2011 were tested by drug fast experiments,and data analysis was used software WHONET 5.4.Results The separation rate of Staphylococcus aureus was 36.95%,Staphylococcus epidermidis was 23.56%,Staphylococcus haemolyticus was 17.14%,Streptococcus pneumoniae was 12.18% and Enterococcus faecalis was 10.17%.The drug fast of MRSA was 45.65%,while methicillin resistant staphycoccus epidermidis and Staphylococcus haemolyticus were 78.13% and 64.77%,and PNSP was 51.65%.The common clinical Gram Positive Coccus had no drug fast over vancomycin.Conclusion The infection of the common clinical Gram Positive Coccus is very common and it is very necessary to choose the proper antibacterial according to the result of the drug fast experiments.