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急性心肌梗死患者急诊经皮冠状动脉介入治疗后NT—proBNP和QRS积分变化及预后
引用本文:魏洪杰,芦涤. 急性心肌梗死患者急诊经皮冠状动脉介入治疗后NT—proBNP和QRS积分变化及预后[J]. 临床荟萃, 2011, 26(23): 2046-2048
作者姓名:魏洪杰  芦涤
作者单位:中国石油天然气集团公司中心医院心内科,河北廊坊,065000
摘    要:目的观察急性心肌梗死(AMI)患者急诊经皮冠状动脉介入治疗(PCI)后血浆N氨基末端脑钠肽前体(NT—proBNP)水平及心电图QRS积分变化情况,探讨其临床意义。方法102例ST段抬高型AMI患者分为急诊PCI组(n=52)和常规药物保守治疗组(非PCI组,n=50),发病24小时采用酶联免疫吸附测定法检测血浆NTproBNP水平,第7天查心电图测定QRS积分、查超声心动图测定左心室舒张末内径(LVEDD)及左心室射血分数(LVEF),比较两组上述指标的差异,分别对血浆NT—proBNP、QRS积分与LVEDD、I,VEF进行相关性分析。结果与非PCI组比较。PCI组患者血浆NT—proBNP水平显著性降低(693.8±273.3)ng/LVS(378.9±183.7)ng/L(P〈0.05),QRS积分显著性降低(6.4±0.5)分VS(5.5±0.4)分(P〈0.01),LVEDD显著性降低(55.5±6.6)mmvs(47.2±5.2)mm(P〈0.01),LVEF显著性增高(46.5±7.9)%VS(58.4±8.8)%(P〈0.01)。血浆NT-proBNP水平与QRS积分呈正相关(r=0.428,P〈0.01),与I,VEDD呈正相关(r=0.421,P〈0.01),与LVEF呈负相关(r=0.402,P〈0.05)。结论血浆NT—proBNP的增高能预测AMI面积及早期心室重构。

关 键 词:心肌梗死  血管成形术  经腔  经皮冠状动脉  心电描记术  超声检查  利钠肽    预后

Changes of plasma N-terminal pro-B-type natriuretic peptide and QRS score in patients of acute myocardial infarction after emergent percutaneous coronary intervention and prognosis
WEI Hong-jie,LU Di. Changes of plasma N-terminal pro-B-type natriuretic peptide and QRS score in patients of acute myocardial infarction after emergent percutaneous coronary intervention and prognosis[J]. Clinical Focus, 2011, 26(23): 2046-2048
Authors:WEI Hong-jie  LU Di
Affiliation:WEI Hong-jie,LU Di Department of Cardiology,CNPC Central Hospital,Langfang 065000,China
Abstract:Objective To investigate the value of plasma N-terminal pro-B-type natriuretic peptide(NT-proBNP) and QRS score in patients of acute myocardial infarction(AMI). Methods 102 AMI patients with ST-segment elevation were divided into primary percutaneous coronary intervention(PCI) group(n=52) and medicine group(n=50),level of plasma NT-proBNP was measured after 24 hours of pain onset,QRS score,left ventricular end-diastolic(LVEDD) and left ventricular ejection fraction(LVEF) were detected on the seventh day.The...
Keywords:myocardial infarction  angioplasty  transluminal  percutaneous coronary  electrocardiography  ultrasonography  natriuretic peptide  brain  prognosis  
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