| 老年人消化性溃疡与慢性萎缩性胃炎的相关性研究 |
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| 引用本文： | 付万发,张汾燕,陶方.老年人消化性溃疡与慢性萎缩性胃炎的相关性研究[J].临床荟萃,2011,26(17):1491-1493. |
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| 作者姓名： | 付万发 张汾燕 陶方 |
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| 作者单位： | 北京老年医院消化科,北京,100095 |
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| 摘 要： | 目的研究老年人消化性溃疡与慢性萎缩性胃炎的相关性。方法对十二指肠溃疡（DU）、胃溃疡（GU）和复合性溃疡（CU）的老年患者胃窦、胃窦胃体交界处和胃体黏膜以及慢性胃炎（CG）患者胃窦黏膜活检标本进行组织学检查,统计各自胃黏膜的萎缩、肠化生、慢性炎症、活动性和幽门螺杆菌（Hp）感染的发生率。结果 DU患者胃窦、胃窦胃体交界处和胃体黏膜的萎缩发生率分别为54.0%、8.0%和16.0%,肠化生发生率分别为19.0%、6.0%和4.0%。其胃窦黏膜肠化生的发生率明显低于相应的GU、CU或CG者。3种消化性溃疡和CG患者均存在胃窦部慢性炎症,且老年消化性溃疡患者胃体部炎症的发生率较高,其胃炎活动性以胃窦部为主,且均较CG者高。结论老年人消化性溃疡均可有胃窦部灶性萎缩和肠化生发生,但DU胃窦黏膜肠化发生率最低,这可能是老年DU患者罹患胃癌危险性较低的原因之一。
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| 关 键 词： | 消化性溃疡 胃炎 萎缩性 螺杆菌 幽门 萎缩 肠化 |
Investigation on relationship between peptic ulcer and chronic atrophic gastritis in geratic patients |
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| FU Wan-fa,ZHANG Feng-yan,TAO Fang.Investigation on relationship between peptic ulcer and chronic atrophic gastritis in geratic patients[J].Clinical Focus,2011,26(17):1491-1493. |
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| Authors: | FU Wan-fa ZHANG Feng-yan TAO Fang |
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| Institution: | FU Wan-fa,ZHANG Feng-yan,TAO FangDepartment of Digestive Disease,Beijing Geratic Hospital,Beijing 100095,China |
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| Abstract: | Objective To investigate the relationship between peptic ulcer and chronic atrophic gastritis.Methods The biopsy specimens of gastric mucosa of antrum,junction of antrum and corpus,and corpus in patients with duodenal ulcer(DU),gastric ulcer(GU),complex ulcer(CU) and antral mucosa in patients with chronic gastritis(CG) were examined by histological stains;and then the incidence and degree of atrophy,intestinal metaplasia,chronic inflammatory activity and Helicobacter pylori(H.pylori) infection were statisti... |
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| Keywords: | peptic ulcer gastritis atrophic helicobacter pylori atrophy metaplasia |
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