| 鼻咽癌组织中EphA2的表达变化及其意义 |
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| 作者姓名： | Zhu G Xiao D Chen Q Zhu Y |
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| 作者单位： | 南京医科大学附属无锡第二人民医院耳鼻咽喉科,江苏无锡,214002 |
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| 基金项目： | 无锡市科技局社会发展计划基金项目(No:CSE01012); 南京医科大学科技发展基金项目(No:07NMUM057) |
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| 摘 要： | 目的:探讨鼻咽癌(NPC)组织中EphA2的表达情况及其与肿瘤发生、发展、侵袭、转移、新生血管生成和预后的相关性.方法:常规免疫组织化学技术检测61例NPC和20例鼻咽部慢性炎症组织中EphA2的表达情况,并分析EphA2的表达与NPC临床病理特征和微血管密度之间的关系.结果:NPC组织EphA2阳性表达率显著高于鼻咽...
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| 关 键 词： | 鼻咽肿瘤 EphA2 转移 血管生成 预后 |
The expression and its potentially clinical significance of EphA2 in nasopharyngeal carcinoma |
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| Zhu G,Xiao D,Chen Q,Zhu Y.The expression and its potentially clinical significance of EphA2 in nasopharyngeal carcinoma[J].Journal of Clinical Otorhinolaryngology,2011,25(18):827-9, 833. |
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| Authors: | Zhu Guochen Xiao Dajiang Chen Qi Zhu Yawei |
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| Institution: | ZHU Guochen XIAO Dajiang CHEN Qi ZHU Yawei (Department of Otolaryngology,the Second Affiliated People's Hospital of Wuxi,Nanjing Medical University,Wuxi,214002,China) |
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| Abstract: | Objective: To observe the expression of EphA2,and investigate its correlation with the development,progression,invasion,metastasis,angiogenesis and prognosis in nasopharyngeal carcinoma(NPC). Method: Immunohistochemical staining was used to determine the expression level of EphA2 protein in 61 cases NPC and 20 cases chronic nasopharyngitis samples.The clinically pathological data and results of follow-up were collected.Microvessel density(MVD) was also measured by immunohistochemical staining method with CD... |
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| Keywords: | nasopharyngeal neoplasms EphA2 metastasis angiogenesis prognosis |
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