Assessment of vasogenic edema in eclampsia using diffusion imaging |
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Authors: | S T Engelter J M Provenzale J R Petrella |
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Institution: | (1) Department of Radiology, Duke University Medical Center 3808, Durham, NC 27710, USA Tel.: 9 19-6 84-72 18 Fax: 9 19-6 84-71 38, US;(2) Division of Neurology, Duke University Medical Center, Durham, North Carolina, USA, US |
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Abstract: | We qualitatively assessed the regional distribution of vasogenic edema in a case of postpartum eclampsia. Although diffusion-weighted
imaging showed no abnormalities, bilateral high signal was seen on T2-weighted images and apparent diffusion coefficient (ADC)
maps. ADC of 1.45 ± 0.10 mm2/s × 10–3 for the posterior cerebral artery (PCA) territory and 1.22 ± 0.12 mm2/s × 10–3 for the watershed areas were significantly higher than those in the territories of the anterior (0.85 ± 0.07 mm2/s × 10–3) and middle cerebral (0.79 ± 0.06 mm2/s × 10–3)arteries (P < 0.05). The predilection of ADC changes within the PCA territory and in a previously undescribed watershed distribution
supports the hypothesis that vasogenic edema in eclampsia is due to hypertension-induced failure of vascular autoregulation.
Received: 8 July 1999 Accepted: 25 April 2000 |
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Keywords: | Magnetic resonance imaging Diffusion imaging Eclampsia Edema vasogenic |
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