血清胆碱脂酶测定对鉴别肝硬化及消化性溃疡并发上消化道出血的意义

目的: 探讨血清胆碱脂酶对鉴别肝硬化失代偿及消化性溃疡并发出血的意义。方法: 回顾性分析肝硬化及消化性溃疡并发出血病例110例,分析其入院时的血清胆碱脂酶值。结果: 肝硬化组血清胆碱脂酶为(98.96+43.15)u/L,消化性溃疡组血清胆碱脂酶为(238.86 ±51.87)u/L,差异有统计学意义(P<0.001)。结论: 血清胆碱脂酶可作为鉴别肝硬化及消化性溃疡并发出血的一简单有效的方法。

Discriminating complicated hemorrhage of liver cirrhosis and peptic ulcer by serum cholinesterase

Objective: This study was designed to characterize the ultrastructure of the coccoid Helicobacter pylori(H. pylori) forms in the tissues of carcinoma.Methods: Transmission electron microscopy(TEM) technique was used to examine the structure of coccoid H. pylori in 4 cases of gastric carcinoma and 2 cases of esophageal carcinoma.Results: It was found that the coccoid H. pylori were scattered in cancer nest and cancer interspace,some of which enterded cancer cells,macrophages and other cells.The coccoid H. pylori appeared to be similar to the L-forms of other bacteria with varying cell shape and size,different cytoplasmic electron densities and defects in cell wall.Two types of coccoid H. pylori could be distinguished in the tissues of carcinoma by TEM.Type A was smaller with higher electron density in the cytoplasma,and flagellation on the cell membrane,suggesting that it could be viable.However,the type B was larger with lower electron density in the cytoplasma,and no flagellation on the cell membrane,suggesting that it could be a degenerative form.Conclusions: The coccoid forms of H.pulori still have certain degree of viability,thus they may play an important role in the transmission of H. pylori,the relapse of H. pylori related disease after treatment and the development of the related carcinoma.