Low prevalence of MODY2 and MODY3 mutations in Brazilian individuals with clinical MODY phenotype |
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| Authors: | Furuzawa Gilberto K Giuffrida Fernando M A Oliveira Carolina S V Chacra Antonio R Dib Sergio A Reis André F |
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| Affiliation: | aMolecular Endocrinology Laboratory/Division of Diabetes, Federal University of São Paulo, Rua Cincinato Braga 59, CJ B2, 01333-011 São Paulo, SP, Brazil |
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| Abstract: | Prevalence of MODY2 and MODY3 mutations has been assessed in 23 Brazilian families with MODY phenotype. Mutations in HNF-1alpha have been found in 3 families (13%) and 2 families (8.7%) had new glucokinase mutations. These genes do not explain the majority of MODY cases in Brazilian population. |
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| Keywords: | Mody Mutations Brazilians |
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