脂蛋白相关磷脂酶A2、缺血修饰蛋白在动脉硬化性脑梗死的应用价值

目的探讨脂蛋白相关磷脂酶A2及缺血修饰蛋白等指标与动脉硬化性脑梗死（ACI）的关系。方法对脑梗死组130例和对照组120例的血清同时进行脂蛋白相关磷脂酶A2（Lp-PLA2）、缺血修饰蛋白（IMA）、同型半胱氨酸（Hcy）、脂蛋白（a）〔Lp（a）〕、超敏C反应蛋白（hs-CRP）项目平行检测,并做对比分析。结果脑梗死组Lp-PLA2、IMA、Hcy、Lp（a）、hs-CRP表达水平及阳性率均高于对照组。结论血清Lp-PLA2、IMA、Hcy、Lp（a）、hs-CRP等水平增高与ACI密切相关,及早检测血清Lp-PLA2、IMA等相关指标,对动脉硬化性脑梗死的预防及治疗有着非常积极的意义。

Application value of lipoprotein-associated phospholipase A2 and ischemia modified albumin in atherosclerotic cerebral infarction

Objective To investigate the relationship between atherosclerosis cerebral infarction（ACI）,the serum level of lipoprotein-associated phospholipase A2 and ischemia modified albumin（IMA）.Methods The serum levels of Lp-PLA2,IMA,Hcy,Lp（a） and hs-CRP were parallelly detected in 130 examples of ACI group and other 120 examples of the control group.The contrastive analysis was conducted.Results Expression levels and positive rates of Lp-LA2,IMA,Hcy,Lp（a） and hs-CRP in ACI group were higher than that in control group.Conclusion The serum levels of Lp-PLA2,IMA,Hcy,Lp（a） and hs-CRP are closely related with cerebrovascular diseases.Detecting the serum levels of Lp-PLA2、IMA、Hcy、Lp（a）and hs-CRP as early as possible has positive significance for preventing and curing cerebrovascular diseases.