| 柠檬萜对豚鼠小肠电活动的调整作用 |
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| 引用本文： | 黄沚荷,杨德治,魏义全,丁霭龄. 柠檬萜对豚鼠小肠电活动的调整作用[J]. 东南大学学报(医学版), 1996, 0(2) |
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| 作者姓名： | 黄沚荷 杨德治 魏义全 丁霭龄 |
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| 作者单位： | 南京铁道医学院生理学教研室 |
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| 摘 要： | 目的：研究柠檬萜对豚鼠小肠电活动的影响。方法：用电生理技术记录以９８％柠檬萜给空腹清醒豚鼠灌胃后小肠消化间期综合肌电的变化。结果：给柠檬萜后，十二指肠及空肠峰电位明显减少（Ｐ＜０．０１，Ｐ＜０．０５）。原先ＩＤＭＥＣ周期不典型或紊乱的峰电位在给药后４０～８０ｍｉｎ，十二指肠和空肠分别有７６％和８２％例次呈现出典型的ＩＤＭＥＣ周期或有出现ＩＤＭＥＣ周期的倾向。结论：柠檬萜可能具有调整豚鼠小肠电活动周期的作用。
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| 关 键 词： | 柠檬萜；豚鼠；小肠；动作电位 |
Regulative Effect of R(+)-Limonene on the Small Intesinal Electric Activities of Guinea-Pigs |
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| Huang Zhihe, Yang Dezhi, Wei Yiquan, Ding Ailing. Regulative Effect of R(+)-Limonene on the Small Intesinal Electric Activities of Guinea-Pigs[J]. Journal of Southeast Univ: Medical Sci Ed, 1996, 0(2) |
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| Authors: | Huang Zhihe Yang Dezhi Wei Yiquan Ding Ailing |
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| Abstract: | OBJECTIVES:To study the effect of R (+)-Limonene on the small intestinal electric activities of tile guinea-pig. METHODS: The electrophysiological technique was applied to record the variation of small intestinal interdigestive myoelectric complex (IDMEC)after instilling 98% R (+ )-Limonene into the stomach of fasted conscious guinea-pigs. RESULTS: After administration of R (+)-Linonene, the number of spilte potential in duodenum and jejunum was decreased sigllificantly (PRO. of;P<0. 05).The standard cycle of IDMEC and tendency toward stalldard cycle were found in 76% of the duodenum alld 82% of the jejunum that had an unstandard cycle of IDMEC or irregular spike potentiell before drugs. CONCLUSIONS: R (+) -Limonene is suggested to regulate the electric activitiy c ycle in the small intestine of guinea-pigs. |
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| Keywords: | R(+)-Limonene guinea-pigs small intestine action potential |
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