| 自制氟碳声学造影剂心肌造影安全性实验研究 |
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| 引用本文： | 朱贤胜,吴晓岩,高云华,杨未晓. 自制氟碳声学造影剂心肌造影安全性实验研究[J]. 中国临床医学影像杂志, 2003, 14(5): 328-329 |
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| 作者姓名： | 朱贤胜 吴晓岩 高云华 杨未晓 |
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| 作者单位： | 1. 广州军区广州总医院超声科,广东,广州,510010
2. 第三军医大学新桥医院超声科,重庆,400037 |
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| 摘 要： | 目的:研究自制的氟碳声学造影剂的安全性。方法:采用谐波触发显像及心内插管对实验犬进行心肌声学造影,观察血流动力学变化,并进行多脏器病理检查。结果:实验中,犬生命征平稳。心肌回声增强,血流动力学无变化,病理检查未见异常改变。结论:自制的氟碳声学造影剂安全、有效,可用于动物实验研究。
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| 关 键 词： | 造影剂 心肌 氟碳化合物 |
| 文章编号： | 1008-1062(2003)05-0328-03 |
The safety experimental study of self-made perfluorocarbon ultrasound contrast agent |
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| ZHU Xian-sheng,WU Xiao-yan,GAO Yun-hua,YANG Wei-xiao. The safety experimental study of self-made perfluorocarbon ultrasound contrast agent[J]. Journal of China Clinic Medical Imaging, 2003, 14(5): 328-329 |
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| Authors: | ZHU Xian-sheng WU Xiao-yan GAO Yun-hua YANG Wei-xiao |
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| Affiliation: | ZHU Xian-sheng,WU Xiao-yan,GAO Yun-hua,YANG Wei-xiao Department of Ultrasonic Diagnosis,Guangzhou General Hospital of Guangzhou Army,Guangzhou510010,China |
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| Abstract: | Objective:To explore the safety of self-made perfluorocarbon ultrasound contrast agent.Methods:Transvenous myocardial contrast echocardiography were performed in7dogs.Transient second harmonic imaging,and intubation within heart were carried out.The changes of hemodynamic and multi-organic pathological examination were observed.Re sults:After transvenous MCE,no hemodynamic changes were found.The echo intensity was augmented,multi-organic pathologic exami-nation was normal.Conclusion:The self-made perfluorocarbon ultrasound contrast agent is safe and efficient and could be used in animal experimentation. |
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| Keywords: | contrast media myocardium Fluorocarbons |
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