| 试纸法检测血液中富组氨酸蛋白Ⅱ快速诊断恶性疟的初步观察 |
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| 引用本文： | 韩广东,崔刚,张洪花,杨宝金.试纸法检测血液中富组氨酸蛋白Ⅱ快速诊断恶性疟的初步观察[J].中国病原生物学杂志,1996(3). |
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| 作者姓名： | 韩广东 崔刚 张洪花 杨宝金 |
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| 作者单位： | 山东省寄生虫病防治研究所，卫生部疾病控制司 |
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| 摘 要： | 本文报道了应用试纸法检测感染恶性疟后血内富组氨酸蛋白Ⅱ，用以诊断恶性疟。对镜检确诊的恶性疟病人进行了检测，阳性检出率为９５％，检测全过程需５～７ｍｉｎ。应用改良法检测全血或血浆仅需２～３ｍｉｎ；同时对间日疟病人血样和非疟疾病人血样进行了检测，结果全部阴性，特异性为１００％。应用试纸法诊断疟疾无须任何仪器，诊断快速、方便，对临床早期确诊病人并给于及时治疗、减少传播和病死率有重要意义。
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| 关 键 词： | 恶性疟 富组氨酸蛋白 检测试纸 诊断 |
AN EXPERIMENTAL TRIAL OF RAPID DIAGNOSIS OF FALCIPARUM MALARIA BY DETECTING HISTIDINE-RICH PROTEIN 2 IN BLOOD WITH A DIPSTICK |
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| Han Guang-Dong, Cui Gang, Zhang Hong-Hua, Yang Bao-Jin.AN EXPERIMENTAL TRIAL OF RAPID DIAGNOSIS OF FALCIPARUM MALARIA BY DETECTING HISTIDINE-RICH PROTEIN 2 IN BLOOD WITH A DIPSTICK[J].Journal of Pathogen Biology,1996(3). |
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| Authors: | Han Guang-Dong Cui Gang Zhang Hong-Hua Yang Bao-Jin |
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| Abstract: | A dipstick test was used to detect histidine-rich protein 2 in samples of blood and plasma from patients with Plasmodium falciparum. The coincidence rate with microscopy was 95%. The reaction of plasma was stronger than that of blood. There was no cross reaction with samples of vivax malaria and healthy human blood. The specificity was 100%. This method is quick, convenient and it does not need any complicated instrument. It is a very useful method for rapid diagnosis, early treatment, effective prevention, as well as the reduction of clinical mortaility. |
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| Keywords: | Falciparum malaria histidine-rich protein 2 dipstick diagnosis |
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