Hypophyseal-gonadal system during male aging |
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Authors: | E V Moroz N S Verkhratsky |
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Affiliation: | Institute of Gerontology, U.S.S.R. Academy of Medical Sciences, Vyshgorodskaya 67, 252655 Kiev 114, U.S.S.R. |
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Abstract: | The concentration of sex and gonadotropic hormones in blood plasma of 280 reasonably healthy men aged 20-105 was determined using radioimmunoassay kits. Compared to men aged 20-39, the statistically significant decrease in testosterone level was registered in men aged 55-59, the increase in oestradiol in men aged 60-64, progesterone in men aged 55-59, and in LH and FSH in the group aged 65-69. The reactivity of central and peripheral links of the hypothalamic-gonadal system to direct and feed-back control influences alters with age. |
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Keywords: | aging sex hormones gonadotropins in men |
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