肠道菌群失调的研究进展

人体肠道内寄居着数量庞大、种类繁多的微生物,统称为肠道菌群。肠道正常菌群参与机体的营养消化吸收、生物拮抗、免疫、抗肿瘤等一系列生命活动并维持机体健康。一旦受到宿主及外环境变化的影响,平衡状态被打破,则会导致肠道菌群失调,进而引发和加重各种疾病。该文就肠道菌群失调的类型、致病因素、临床表现、相关疾病及治疗等的研究进展进行综述。

Research Progress of Intestinal Dysbacteriosis

The human gut harbours a myriad of different microbes known together as the intestinal flora. Normal intestinal flora plays an important role in digestion and absorption of nutrients, biological antagonism, immune response,antitumor activity to keep the body health. It will not only lead to intestinal dysbacteriosis but also induce and aggravate various diseases when the balance of the intestinal flora is disturbed by host and external environment change. Here is to make a review of the research progress in classification patho- genic factors,clinical manifestations,related diseases and therapeutic regimen of dysbacieriosis.