Molecular control of nitric oxide synthases in the cardiovascular system |
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| Authors: | Papapetropoulos A Rudic R D Sessa W C |
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| Affiliation: | Department of Pharmacology, Boyer Center for Molecular Medicine, Yale University School of Medicine, New Haven, CT 06536, USA. |
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| Abstract: | Nitric oxide plays an important role in cardiovascular homeostasis. In this review, the regulation of the three nitric oxide synthase isoforms in the cardiovascular system are examined at molecular and cellular levels. In addition, recent information gleaned from the use of NOS knockout mice are discussed. |
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