暴发性胰腺炎死亡原因分析

目的　探讨暴发性胰腺炎(FAP)患者死亡原因。方法　回顾性分析宣武医院1992年6月至2004年7月收治的30例FAP死亡患者的临床资料,对其死亡原因及时间、临床特点进行分析。结果　FAP患者病死率为50.85%,多器官功能障碍综合征(MODS)是FAP患者死亡的主要原因,其次为全身感染、胰腺脓肿腐蚀血管所致腹腔内大出血、失血性休克等。FAP患者早期病死率高,发病7天内死亡16例,占53.33%。结论　FAP的特点是早期病死率高、预后差。预防及早期治疗MODS,适时手术是降低FAP患者病死率的关键。

Analysis of Death Causes of Fulminant Acute Pancreatitis

Objective To investigate the death causes of patients with fulminant acute pancreatitis(FAP). Methods The clinical data of 30 d patients with FAP admitted to Xuanwu hospital from June 1992 to July 2004 were reviewed and causes of death, clinical characteristics were analyzed. FAP was defined as presence of organ dysfunction within 72 h after onset of symptoms. Results The mortality rate of FAP was 50.85%, MODS was the main cause of FAP. Mortality rate was high in FAP early, sixteen FAP patients died within 7 d after onset of symptoms(53.33%). Conclusion The characteristic of FAP is high early mortality rate and poor prognosis. To treat MODS early and operate early are the key to reduce mortality of FAP.