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Fatal septic complication of transcatheter chemoembolization for hepatocellular carcinoma |
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| Authors: | Toru Hashimoto M.D. Takashi Mitani Hironobu Nakamura Shinichi Hori Takahiro Kozuka Yasuo Kobayashi Atsuyuki Nakata Takahiro Tsujimura |
| Affiliation: | (1) Department of Radiology, Osaka University Medical School, 2-2, Yamadaoka, 565 Suita-shi, Osaka, Japan;(2) Department of Radiology, Sumitomo Hospital, 5-2-2 Nakanoshima, Kita-ku, 530 Osaka, Japan;(3) Department of Internal Medicine, Sumitomo Hospital, 5-2-2 Nakanoshima, 530 Kita-ku Osaka, Japan;(4) Department of Pathology, Sumitomo Hospital, 5-2-2 Nakanoshima, 530 Kita-ku Osaka, Japan |
| Abstract: | A patient with hepatocellular carcinoma, associated segmental portal vein thrombosis, and accompanying pneumobilia, developed a liver abscess and sepsis following transcatheter chemoembolization (TCE). It was believed that the combination of bile duct necrosis after arterial occlusion and pneumobilia led to ascending enteric infection and seeding of the necrotic tumor, which ultimately led to fatal outcome. We conclude that TCE is contraindicated in such cases. |
| Keywords: | Hepatocellular carcinoma Chemoembolization, complications Liver abscess Pneumobilia Portal vein thrombosis |
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