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比索洛尔和依那普利对高血压病治疗的比较观察
引用本文:牛列智,马锦玲,伏静媛,彭小兰,叶青,宁金氏,滕青平,王银娣,赵毅,吴俊兰. 比索洛尔和依那普利对高血压病治疗的比较观察[J]. 中国循环杂志, 1994, 0(8)
作者姓名:牛列智  马锦玲  伏静媛  彭小兰  叶青  宁金氏  滕青平  王银娣  赵毅  吴俊兰
作者单位:甘肃省兰州市第一医院心内科
摘    要:对145例原发性高血压患者分组应用比索洛尔(Bisoprolol)与依那普利(Enalapril)治疗,以观察各自疗效。结果显示:①比素洛尔总有效率87.5%,依那普利总有效率78.7%,两者疗效有明显差异。②对心率、血脂、血糖、血清电解质、血像和肝肾功能观察期间均无不良影响。③比索洛尔每晨只服1次即可维持疗效,使用方便,副作用小,耐受性好。

关 键 词:高血压,比索洛尔,依那普利

EFFECT OF BISOPROLOL ON ESSENTIAL HYPERTENSION
Niu Lie-Zhi,Ma Jin-Ling, Fu JingYuan,et al.. EFFECT OF BISOPROLOL ON ESSENTIAL HYPERTENSION[J]. Chinese Circulation Journal, 1994, 0(8)
Authors:Niu Lie-Zhi  Ma Jin-Ling   Fu JingYuan  et al.
Abstract:The therapeutic effects of bisoprolol (max. dose 15 mg/d,4 wks) and enalapril (max. dose 40 mg/d,4 wks) were studied in 69 and 76 essential hypertensives, respectively with age, sex and stages of hypertension grossly matched. The results showed that the total effective rates in bisoprolol and enalapril were 87.5% and 78.7% (p<0.01), respectively; no serious side effects were observed and bisoprolol was well tolerated. Bisoprolol is effective and safe in patients with essential hypertension and is better accepted by patients because of its longer duration of antihypertensive action.
Keywords:Essential hypertension  Bisoprolol  Enalapril  
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