| 南京地区1285例男性不育患者细胞遗传学分析 |
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| 引用本文： | 吴星,朱海燕,朱瑞芳,张颖.南京地区1285例男性不育患者细胞遗传学分析[J].中国优生与遗传杂志,2011(12):45-46. |
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| 作者姓名： | 吴星 朱海燕 朱瑞芳 张颖 |
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| 作者单位： | 南京大学医学院附属鼓楼医院遗传室; |
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| 基金项目： | 江苏省医学分子技术重点实验室(KL002) |
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| 摘 要： | 目的对临床诊断为男性不育症患者进行细胞遗传学分析,探讨男性不育症与染色体之间的关系。方法常规方法制备外周血染色体标本,G显带。结果对男性不育症患者1285例进行染色体核型分析,共发现135例异常,异常率10.5%。结论染色体异常是造成男性不育的重要遗传因素,对精液检查异常者或男性性征发育不良者进行染色体检查,将有助于不育病因的诊断。
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| 关 键 词： | 男性不育 染色体 异常核型 |
Analysis of chromosomal karyotypes in 1285 cases of male infertility in Nanjing area |
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| WU Xing,ZHU Hai-yan,ZHU Rui-fang,ZHANG Ying..Analysis of chromosomal karyotypes in 1285 cases of male infertility in Nanjing area[J].Chinese Journal of Birth Health & Heredity,2011(12):45-46. |
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| Authors: | WU Xing ZHU Hai-yan ZHU Rui-fang ZHANG Ying |
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| Institution: | WU Xing,ZHU Hai-yan,ZHU Rui-fang,ZHANG Ying.(Department of Genetics,Gulou Hospital Affiliated to Medical College,Nanjing University,Nanjing 210008,China) |
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| Abstract: | Objective: To make a cytogenetics study of clinically diagnosed male infertility,and to study the relationship between chromosomal abnormalities and male infertility.Methods: Chromosomal preparations made from peripheral blood lymphocytes by conventional,G banding techniques in all cases.Results: 135 cases of chromosomal abnormalities were checked out from 1285 total cases and the abnormal rate was 10.5%.Conclusions: The chromosomal anomalies are important inheritance factor for male sterility.Chromosomal a... |
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| Keywords: | Male infertility Chromosome Abnormal karyotype |
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