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羊水中白细胞介素-8水平与绒毛膜羊膜炎的关系
引用本文:郑艳,颜和芳,庄文燕.羊水中白细胞介素-8水平与绒毛膜羊膜炎的关系[J].中国优生与遗传杂志,2011(5):58-59.
作者姓名:郑艳  颜和芳  庄文燕
作者单位:龙岗中心医院妇产科;
摘    要:目的探讨胎膜早破孕妇羊水中白细胞介素-8(IL-8)水平与绒毛膜羊膜炎的关系。方法用酶联免疫法(ELISA法)测定62例胎膜早破孕妇和46例正常足月妊娠未临产孕妇羊水中IL-8浓度;病理检查两组分娩后的胎膜组织,确定有无绒毛膜羊膜炎。结果胎膜早破组羊水中IL-8浓度高于对照组(P〈0.05),破膜时间超过24h其羊水中IL-8水平明显高于破膜时间小于12h内的患者,绒毛膜羊膜炎组羊水中IL-8浓度高于对照组(P〈0.05)。结论胎膜早破及绒毛膜羊膜炎孕妇羊水中IL-8水平显著升高,可作为绒毛膜羊膜炎的早期诊断指标。

关 键 词:绒毛膜羊膜炎  白细胞介素-8  胎膜早破  羊水

Relationship between interleukin-8 in amniotic fluid and chorioamnionitis
ZHENG Yan,YAN He-fang,ZHUANG Wen-yan..Relationship between interleukin-8 in amniotic fluid and chorioamnionitis[J].Chinese Journal of Birth Health & Heredity,2011(5):58-59.
Authors:ZHENG Yan  YAN He-fang  ZHUANG Wen-yan
Institution:ZHENG Yan,YAN He-fang,ZHUANG Wen-yan.(Department of Gynecology,Longgang Central Hospital,Shenzhen Guangdong,518116,China)
Abstract:Objective:To investigate the relationship between interlerkin-8(IL-8) levels in the amniotic fluid and the chorioamnionitis in pregnant women with premature rupture of membranes.Methods: Enzyme-linked immunosorbent assay(ELISA) was used to measure the IL-8 concentration in amniotic fluid in 62 pregnant women with premature ruptrue of membranes and in 46 pregnant women with normal term pregnancy before parturient.In the two groups,the fetal membranes post-partum were kept for pathology examination to prove t...
Keywords:Chorioamnionitis  Interleukin-8  Premature rupture of membranes  Amniotic fluid  
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