| 369例男性不育症患者的染色体核型分析 |
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| 引用本文： | 姚妍怡,宋婕萍,王波,徐淑琴,郭淮. 369例男性不育症患者的染色体核型分析[J]. 中国优生与遗传杂志, 2011, 0(9): 58-59 |
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| 作者姓名： | 姚妍怡 宋婕萍 王波 徐淑琴 郭淮 |
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| 作者单位： | 湖北省妇幼保健院检验遗传中心; |
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| 摘 要： | 目的探讨男性不育与染色体核型异常的关系。方法按照精液常规检查结果,将369例男性不育症患者分为4组(无精子症组61例,少精子症组98例,弱精子症组117例,精液正常组93例),采用常规外周血淋巴细胞染色体制备方法对上述患者进行细胞遗传学检测。结果染色体异常检出率为8.4%(31/369),其中无精子症组19.7%(12/61),少精子症组7.1%(7/98),弱精子症组6.0%(7/117),精液正常组5.4%(5/93)。结论染色体异常是男性不育的主要遗传因素。
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| 关 键 词： | 男性不育 染色体 核型分析 |
Analysis of chromosomal abnormalities for male infertility in 369 cases. |
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| YAO Yan-yi,SONG Jie-ping,WANG Bo,et al.. Analysis of chromosomal abnormalities for male infertility in 369 cases.[J]. Chinese Journal of Birth Health & Heredity, 2011, 0(9): 58-59 |
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| Authors: | YAO Yan-yi SONG Jie-ping WANG Bo et al. |
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| Affiliation: | YAO Yan-yi,SONG Jie-ping,WANG Bo,et al.(The Laboratory Genetic Center,Hubei Province Woman and Child Health Care Hospital,Wuhan,430070) |
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| Abstract: | Objective: To investigate the relationship between male infertility and chromosome abnormalities.Methods: According to Semen Test results,we divided 369 male infertile patients into 4 groups(61 cases of azoospermia,98 cases of oligospermia,117 cases of astenozoospermia and 93 cases of semen normal patients),and examined their periphery blood lymphocyte culture by chromosomal karyotype analysis.Results: The chromosomal abnormality detection rate was 8.4%(31/369),of which 19.7% of azoospermia group(12/61),oli... |
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| Keywords: | Male infertility Chromosome Karyrotype analysis |
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