| sICAM-1在妊娠期高血压疾病患者的变化和临床意义 |
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| 引用本文： | 刘爱敏. sICAM-1在妊娠期高血压疾病患者的变化和临床意义[J]. 中国优生与遗传杂志, 2011, 0(5): 54-54,45 |
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| 作者姓名： | 刘爱敏 |
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| 作者单位： | 青岛市妇女儿童医疗保健中心; |
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| 摘 要： | 目的探讨可溶性细胞间粘附分子-1(sICAM-1)在妊娠期高血压疾病(HDCP)患者血浆中的变化及其临床意义。方法研究对象包括33例妊娠期高血压疾病患者(其中子痫前期13例、妊娠期高血压20例),20例正常妊娠妇女(均为孕32-35周)和25例正常未孕妇女,应用酶联免疫吸附试验(ELISA)测定各组研究对象血浆中的sICAM-1水平。结果 sIACM-1未孕组443.68±235.17ng/ml,正常妊娠组664.67±287.33 ng/ml,两者性比差异有统计学意义(P<0.05);与正常妊娠组比较,妊娠期高血压组1145.46±326.67 ng/ml,差异有统计学意义(P<0.05);子痫前期组1402.89±354.67 ng/ml,明显高于正常妊娠组,差异均具有统计学意义(P<0.01);与妊娠高血压组比较差异有显著性(P<0.05)。结论外周血中sICAM-1水平变化与妊娠期高血压疾病(HDCP)密切相关,随着病情加重sICAM-1值明显升高,提示sICAM-1水平上调与妊娠期高血压疾病的发生有关。
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| 关 键 词： | 可溶性细胞间粘附分子-1 妊娠期高血压疾病 |
The changes and clinical significance of pregnancy induced hypertension in patients with sICAM-1 |
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| LIU Ai-min.. The changes and clinical significance of pregnancy induced hypertension in patients with sICAM-1[J]. Chinese Journal of Birth Health & Heredity, 2011, 0(5): 54-54,45 |
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| Authors: | LIU Ai-min. |
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| Affiliation: | LIU Ai-min.(Qingdao Center for Women and Children Health Care,266012) |
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| Abstract: | Objective:To investigate the soluble intercellular adhesion molecule-1(sICAM-1) in hypertensive disorder complicating pregnancy(HDCP) changes in the plasma of patients and their clinical significance.Methods:The subjects included 33 pregnant women with hypertensive disorders(including 13 cases of preeclampsia,gestational hypertension in 20 cases),20 normal pregnant women(both pregnant 32-35 weeks) and 25 cases of normal non-pregnant women,enzyme-linked immunosorbent assay(ELISA) measured in each group studi... |
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| Keywords: | Soluble intercellular adhesion molecule-1 Pregnancy induced hypertension |
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