| 血清胱抑素C在高胆红素血症新生儿肾损害中的意义 |
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| 引用本文： | 高琳,陈文举,赖卫强,周勇,苏谦.血清胱抑素C在高胆红素血症新生儿肾损害中的意义[J].中国优生与遗传杂志,2011(7):87-88. |
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| 作者姓名： | 高琳 陈文举 赖卫强 周勇 苏谦 |
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| 作者单位： | 台州市中心医院检验科; |
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| 摘 要： | 目的评价血清胱抑素C（CysC）在高胆红素血症患儿肾损害中的意义。方法收集54例新生儿高胆红素血症患儿（轻度黄疸组19例,中重度黄疸组35例）和20例正常足月新生儿的血清,以生化分析法测定总胆红素（TBIL）、胱抑素C（CysC）、尿素氮（BUN）、肌酐（SCr）含量,并进行相关的统计学分析。结果中重度黄疸组CysC、BUN、SCr浓度明显高于轻度黄疸组和正常对照组（P〈0.05）;中重度黄疸组CysC的异常率显著高于BUN和SCr的异常率（P〈0.05）。结论血清CysC是评价高胆红素血症新生儿早期肾损害一项敏感可靠的指标。
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| 关 键 词： | 胱抑素C 新生儿 高胆红素血症 肾功能损害 |
Serum cystatin C as an renopathy markers for neonates with hyperbilirubinemia. |
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| GAO Lin,CHEN Wen-ju,LAI Wei-qiang,ZHOU Yong,SU Qian..Serum cystatin C as an renopathy markers for neonates with hyperbilirubinemia.[J].Chinese Journal of Birth Health & Heredity,2011(7):87-88. |
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| Authors: | GAO Lin CHEN Wen-ju LAI Wei-qiang ZHOU Yong SU Qian |
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| Institution: | GAO Lin,CHEN Wen-ju,LAI Wei-qiang,ZHOU Yong,SU Qian.(Department of Laboratory Medicine,Taizhou Central Hospital,Taizhou 318000,China) |
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| Abstract: | Objective: To evaluate the value of cystatin C(CysC) in impairment of renal function in neonates with hyperbilirubinemia.Methods: Fifty-four neonates with hyperbilirubinemia(19 cases of mild jaundice and 35 cases of moderately severe jaundice) and 20 full-term newborn infants were enrolled.CysC,TBIL,BUN and SCr were assayed using biochemical method.Results: The level of CysC,BUN and SCr in moderately severe jaundice group were significantly higher than mild jaundice group and normal group(P<0.05).The abnorm... |
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| Keywords: | Cystatin C Neonate Hyperbilirubinemia Kidney dysfunction |
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