| 脐血促酰化蛋白水平测定与胎儿发育临床意义研究 |
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| 引用本文： | 郑俊虎,冯维良,郑骆颖,杜文君,林锋,王靖.脐血促酰化蛋白水平测定与胎儿发育临床意义研究[J].中国优生与遗传杂志,2011(8):59-60,91. |
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| 作者姓名： | 郑俊虎 冯维良 郑骆颖 杜文君 林锋 王靖 |
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| 作者单位： | 瑞安市人民医院妇幼分院新生儿科; |
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| 基金项目： | 温州市科技计划项目(Y20080048); 瑞安市科技计划项目(20082087) |
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| 摘 要： | 目的探讨脐血促酰化蛋白(ASP)水平与胎儿生长发育的关系。方法研究对象为大于胎龄儿(LGA)、适于胎龄儿(AGA)和小于胎龄儿(SGA)各30例。应用酶联免疫吸附法(ELISA)测定血浆促酰化蛋白和脂联素浓度,用免疫比浊法测定甘油三酯(TG)、总胆固醇(TCH)、低密度脂蛋白-胆固醇(LDL-c)、高密度脂蛋白-胆固醇(HDL-c)的水平;并分析脐血促酰化蛋白水平与脐血脂联素水平、母血促酰化蛋白水平、新生儿性别、出生体质量、体质量指数、胎盘重量和血脂水平的相关性。结果①LGA的脐血ASP水平高于AGA,AGA的脐血ASP水平高于SGA,差异有统计学意义(P<0.001),三组新生儿血脂水平差异无统计学意义(P>0.05)。②脐血ASP水平与新生儿出生体质量、BM、I脐血甘油三酯水平呈显著正相关(P<0.001),与血脂联素水平呈显著负相关(P<0.001),与母血ASP水平、胎盘重量无相关性(P>0.05)。③男、女婴脐血ASP、血脂各成分水平比较差异均无统计学意义(P>0.05)。结论促酰化蛋白参与胎儿生长发育调节,脐血ASP水平可反映胎儿的生长发育状况。
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| 关 键 词： | 促酰化蛋白 胎儿 血脂 体质指数 脐血 |
Plasma acylation-stimulating protein level of cord blood and its fetal growth significance |
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| ZHENG Jun-hu,FENG Wei-liang,ZHENG Luo-yin,DU Wen-jun,LIN Feng,WANG Jing..Plasma acylation-stimulating protein level of cord blood and its fetal growth significance[J].Chinese Journal of Birth Health & Heredity,2011(8):59-60,91. |
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| Authors: | ZHENG Jun-hu FENG Wei-liang ZHENG Luo-yin DU Wen-jun LIN Feng WANG Jing |
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| Institution: | .(Department of Neonatoloty,People′s Hospital of Rui′an,Maternal and Child Health Hospital of Rui′an Zhejiang,325200) |
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| Abstract: | Objective:To investigate the relationship between plasma acylation-stimulating protein(ASP) and growth and development among fetus.Methods:In the present study,30 LGA infants,30 AGA infants and 30 SGA infants were enrolled in.The concentration of ASP and serum adiponectin in plasma were measured by ELISA.Serum TG,TCH,LDL-c and-HDL-c were assayed with turbidimetry.the correlation between cord plasma ASP and adiponectin,matemal plasma ASP,newborn gender,birth weight,BMI,placental weight and blood lipids were ... |
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| Keywords: | Acylation-stimulating protein Fetus Blood fat Body mass index Cord blood |
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