| 新生儿高胆红素血症G6PD缺乏症筛查及临床意义 |
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| 引用本文： | 邓春红,肖朝霞,吴仲环. 新生儿高胆红素血症G6PD缺乏症筛查及临床意义[J]. 中国优生与遗传杂志, 2011, 0(9): 97-98 |
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| 作者姓名： | 邓春红 肖朝霞 吴仲环 |
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| 作者单位： | 广东省韶关市妇幼保健院儿科; |
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| 摘 要： | 目的探讨葡萄糖6磷酸脱氢酶（G6PD）缺乏与新生儿高胆红素发生率及发病时间的关系,为高胆的临床诊断及治疗提供科学依据。方法对2008年1月至2009年12月在韶关市妇幼保健院分娩的活产新生儿采用荧光斑点法对其进行G6PD筛查,对G6PD缺乏的患儿,按姓别分组调查其高胆发生率及发病时间。结果 G6PD缺乏的患儿高胆发生率显著高于对照组新生儿;男性高胆发生率显著高于女性;G6PD缺乏的患儿的发病时间主要在生后一用周内。结论 G6PD缺乏为新生儿高胆的重要病因,发病率男性高于女性,发病高峰在出生2～4天,对G6PD缺乏的高胆患儿进行早期干预,能有效减轻G6PD缺乏新生儿溶血的程度和避免发生核黄疸。
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| 关 键 词： | 葡萄糖-6-磷酸-脱氢酶 高胆红素血症 新生儿 筛查 |
The G-6-PD screening and clinical significance for neonatal hyperbibirubinemia. |
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| DENG Chun-hong,XIAO Zhao-xia,WU Zhong-huan.. The G-6-PD screening and clinical significance for neonatal hyperbibirubinemia.[J]. Chinese Journal of Birth Health & Heredity, 2011, 0(9): 97-98 |
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| Authors: | DENG Chun-hong XIAO Zhao-xia WU Zhong-huan. |
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| Affiliation: | DENG Chun-hong,XIAO Zhao-xia,WU Zhong-huan.(Department of Pediatrics,Hospital of Maternal and Child Health of Shaoguan in Guangdong,Shaoguan 512026,China) |
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| Abstract: | Objective:To investigate the relationship between glucose-6-phosphatedehydrogenase(G6PD).Deficiency and the incidence and the incident time of neonatal hyperbibirubinemia and provide the science evdience for clinial diagnosis and teeatment.Methods: Neonatal who born in our hospital in 2008.1-2009.12 were collected for the G-6-PD.Screening with fluoresence spot test.The children lack of G-6-PD activity were divided by sex and investigated the incidence and the incidence time of hyperbibirubinemia.Results: Th... |
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| Keywords: | Glucose-6-phosphatedehydrogenase Hyperbibirubinemia New born Screening |
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