| 基于肺表面活性物质的临床价值对新生儿呼吸窘迫症的治疗新探讨 |
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| 引用本文： | 夏宁,杨代秀,尹同进,徐巧兰,刘立民. 基于肺表面活性物质的临床价值对新生儿呼吸窘迫症的治疗新探讨[J]. 中国优生与遗传杂志, 2011, 0(12): 93-94,40 |
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| 作者姓名： | 夏宁 杨代秀 尹同进 徐巧兰 刘立民 |
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| 作者单位： | 江苏省盐城市第三人民医院儿科; |
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| 摘 要： | 目的探讨肺表面活性物质（PS）珂立苏（Calsurf）治疗新生儿呼吸窘迫症的临床疗效。方法将42例生后确诊为新生儿呼吸窘迫症（NRDS）患儿分为2组,其中对照组21例给予机械通气治疗,治疗组21例在机械通气治疗基础上使用珂立苏治疗。比较2组治疗前后的临床表现、血气分析结果及胸片的变化。结果治疗组在应用珂立苏后皮肤迅速转红,用药6 h后PaO2、a/APO2、PaO2/FiO2均明显提高,PaCO2下降,pH上升,用药24h、3d,PaO2和a/APO2仍在较高水平,与对照组比较,差异均有显著意义（P〈0.05或P〈0.01）。胸部X线显示治疗组肺野透亮度改善与对照组比较,差异有显著意义（P〈0.05）。2组治疗后,治疗组存活19例（90.4%）,对照组存活12例（57.1%）,2组存活率相比,差异有显著性意义（P〈0.05）。结论肺表面活性物质能快速、有效地改善NRDS患儿肺通气、换气功能。
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| 关 键 词： | 呼吸窘迫综合征 新生儿 肺表面活性物质 |
Based on lung surface active material of the clinical value of neonatal respiratory distress syndrome treadment of the new discussion |
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| XIA Ning,YANG Dai-xiu,YIN Tong-jin,LIU Li-ming.. Based on lung surface active material of the clinical value of neonatal respiratory distress syndrome treadment of the new discussion[J]. Chinese Journal of Birth Health & Heredity, 2011, 0(12): 93-94,40 |
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| Authors: | XIA Ning YANG Dai-xiu YIN Tong-jin LIU Li-ming. |
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| Affiliation: | XIA Ning,YANG Dai-xiu,YIN Tong-jin,LIU Li-ming.(Department of Pediatries Yancheng Hospital Affiliated to Southeast University,Jiangsu Yancheng 224001) |
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| Abstract: | Objective: To explore the clinical therapeutic effect of Calsurf for neonatal respiratory distress syndrome(NRDS).Methods: Forty-two neonates diagnosed after birth was divided into 2 groups.One group was given ventilation from the breathing machine while the other group received Calsurf in addition to ventilation.The clinical manifestation,the results of analysis of the Ph,PaO2,PaCO2 and the change of the chest radiography after treatment in the two groups were compared.Results In the therapeutic group,the ... |
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| Keywords: | Neonatal respiratory distress syndrome Neonate Calsurf |
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