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灌服葛根水煎剂对小鼠抗体激发及IL-2的影响
引用本文:马杰,程桂芝,李丹,刘辉.灌服葛根水煎剂对小鼠抗体激发及IL-2的影响[J].中药材,2002,25(10):731-732.
作者姓名:马杰  程桂芝  李丹  刘辉
作者单位:大连医科大学,大连,116027
摘    要:本文探讨了葛根对机体免疫反应的影响及作用机理。给小鼠以葛根水煎剂灌胃并设置对照组,分别用羊红细胞和卵清蛋白为抗原激发小鼠免疫系统并检测其抗体生成水平,同时比较两组血清中IL-2的浓度。结果给药组SRBC抗体生成水平和卵清抗体生成水平显著高于对照组(P<0.05),两组血清中IL-2的变化无显著差异。提示葛根水煎剂对小鼠机体抗体生成具有促进作用。

关 键 词:葛根  免疫调节剂  IL-2
修稿时间:2002年4月18日

The Effects of Radix Puerariae Decoction on Levels of Antibody and Interleukin-2 in Mice
Ma Jie,Cheng Guizhi,Li Dan,Liu Hui.The Effects of Radix Puerariae Decoction on Levels of Antibody and Interleukin-2 in Mice[J].Jorunal of Chinese Medicinal Materials,2002,25(10):731-732.
Authors:Ma Jie  Cheng Guizhi  Li Dan  Liu Hui
Institution:Dalian Medical University, Dalian 116027.
Abstract:Objective: To study the effects of Radix Puerariae on immune response. Method: Decoction of Radix Puerariae was administrated to mice (ig.), and then sheep red blood cell (SRBC) and ovalbumin were used as antigens. Levels of anti-SRBC,anti-ovalbumin antibodies and serum interleukin-2 (IL-2) were determined. Result: Levels of anti-SRBC, anti-ovalbumin antibodies were higher in experimental group than that in control group (P<0.05), while concertrations of IL-2 showed no significant difference. Conclusion: Decoction of Radix Puerariae can promote the formation of antibody.
Keywords:Radix Puerariae  Immunoregulation  Interleukin-2(IL-2)
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