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Bioequivalent or Nonbioequivalent?
Authors:Aldo Rescigno   Jean Powers  Edward E. Herderick
Affiliation:Stillwater, MN 55082-9278, USA
Abstract:The current tests for bioequivalence are based on assumptions that are not valid in general; this paper shows why it is necessary to use a method that does not depend upon assumptions that cannot, and need not, be proved in general.
Keywords:bioequivalence   rate of absorption   AUC   cmax   exposure
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