Common clinical manifestations of serotonin deficiency and intoxication syndrome |
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| Authors: | A. P. Simonenkov V. D. Fedorov |
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| Affiliation: | (1) Center for Investigation of the Role of Serotonin in the Body, A. V. Vishnevskii Institute of Surgery, Russian Academy of Medical Sciences, Moscow |
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| Abstract: | Clinical manifestations of serotonin deficiency, its genesis, diagnostics, and treatment are described. the contribution of free hemoglobin and myoglobin to the genesis of absolute serotonin deficiency — disseminated intravascular coagulation (DIC) syndrome — is shown. Evidence is presented suggesting that chronic serotonin deficiency underlies aged-related and diabetic angiopathies. It is demonstrated that the serotonin deficiency syndrome has common clinical manifestations with the intoxication syndrome. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 123, No. 6, pp. 604–613, June, 1997 |
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| Keywords: | serotonin serotonin-ferroprotein receptors serotonin deficiency syndrome smooth muscle insufficiency intoxication syndrome DIC syndrome |
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