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四川省63例HIV抗体检测结果不确定者的追踪分析
引用本文:袁丹,魏东兵,余佳,梁姝,周更生,秦光明,刘红露.四川省63例HIV抗体检测结果不确定者的追踪分析[J].预防医学情报杂志,2009,25(6):402-404.
作者姓名:袁丹  魏东兵  余佳  梁姝  周更生  秦光明  刘红露
作者单位:四川省痰病预防控制中心艾滋病确证中心实验室,四川,成都,610041
基金项目:中国第四轮全球基金艾滋病项目 
摘    要:目的分析造成HIV抗体不确定的可能因素,预测HIV抗体不确定者抗体进展情况。方法对HIV筛查阳性样本进行免疫印迹试验(WB)确认,对结果为HIV抗体不确定的检测者进行随访检测并对结果进行分析。结果不同人群,不同带型的检测者在进行复检时阳性率不同。临床期患者抗体滴度很低,确认为不确定时,病毒载量结果却很高。结论处于窗口期感染者、临床期患者以及处于某些特定时期的正常人群等都有可能导致HIV抗体检测出现不确定结果,必要时应结合其他检测方法,如病毒载量检测等,以及流行病学调查辅助做出准确的诊断。

关 键 词:HIV  不确定  病毒载量

Analyse on Track of Indeterminate Results of HIV Antibody Test in Sichuan Province
Institution:YUAN Dan, WEI Dong-bing, YU Jia, et al. (Sichuan Center for Disease Control and Prevention, Chengdu 610041, Sichuan Province, China. )
Abstract:Objective To analyze the possible reasons causing the indeterminate in HIV antibody detection, to predict the antibody amount for the patient with not sure result. Method Samples positive in primary screening test were confirmed with Western blot (WB). Samples with not sure WB results were followed-up and some of them were tested by virus loading test. Result Positive rates of retest are different in different populations, subjects with different blot patterns. Virus load would be high with the clinic patients while the WB result was indeterminate. Conclusion HIV infections staying at window period, stepping into clinic period, normal mass in special time period, such as pregnancy are principle reasons causing the indeterminate result in confirmation test. So, when necessary, it's important to take other methods, such as virus loading test, and epidemic survey to help making a conclusion.
Keywords:HIV
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