MRI增强T1高分辨力各同性容积激发序列与TSE T1W序列检出椎体转移瘤的对比分析

目的 比较增强MRI快速T1高分辨力各向同性容积激发（THRIVE）序列和TSE序列T1W检出椎体转移瘤的价值。方法 对31例经穿刺活检病理证实的椎体转移瘤患者行MR增强检查，增强后先后行常规矢状位TSE T1W序列和矢状位THRIVE序列扫描。比较2个序列显示转移瘤病灶的数目、SNR、CNR和病灶边缘清晰度、运动伪影评分。结果 TSE T1W序列和THRIVE序列扫描时间分别为2 min 55 s和33 s。增强后THRIVE序列显示病灶的数量与TSE T1W序列差异无统计学意义（Z=-0.816，P=0.414）。增强后THRIVE序列的SNR（432.54±271.60）、CNR（233.27±197.65）均低于TSE T1W序列的SNR（674.32±375.79）、CNR（312.38±207.49），差异均有统计学意义（t=-4.366、-2.660，P<0.001、0.012）。TSE T1W序列显示病灶边缘较THRIVE序列清晰（Z=-4.082，P<0.001），但运动伪影较THRIVE序列明显（Z=2.291，P=0.022）。结论 增强扫描THRIVE序列扫描时间短，运动伪影少，椎体转移瘤的检出数目与TSE T1WI序列相当，在椎体转移瘤的检查中取代TSE T1W序列具有可行性。

Comparative analysis of detection of spinal metastases with contrast-enhanced MRI T1 high resolution isotropic volume excitation and TSE T1WI sequence

Objective To compare the usefulness of contrast-enhanced T1 high resolution isotropic volume excitation (THRIVE) sequence and fat-saturated TSE sequence in detection of spinal metastases. Methods Thirty-one consecutive patients with spinal metastases were recruited. All patients received post-contrast TSE T1WI followed by a fat-suppressed THRIVE sequence. The number of lesions, SNR and CNR for both sequences, and the scoring of image quality concerning motion-artifact and tumor conspicuity were compared. Results Acquisition time of the post-contrast TSE T1W sequence and the THRIVE sequence was 2 min 55 s and 33 s, respectively. No significant difference was found in the number of lesions detected between the two sequences (Z=-0.816, P=0.414). The SNR (432.54±271.60) and CNR (233.27±197.65) of the THRIVE sequence were significantly lower than the SNR (674.32±375.79) and CNR (312.38±207.49) of the TSE T1W sequence respectively (t=-4.366, -2.660, P<0.001, 0.012). Tumor conspicuity of the post-contrast TSE sequence was better than that of THRIVE sequence (Z=-4.082, P<0.001), while the motion-artifact in TSE sequence was more severe (Z=2.291, P=0.022). Conclusion The post-contrast THRIVE sequence is capable of decreasing acquisition time and motion-artifact. Besides, its detected efficacy is equal to that of TSE sequence. There is practical possibility to replace the conventional post-contrast TSE T1WI sequence with the THRIVE sequence in the imaging of spinal metastases.