COMPARISON OF RESPIRATORY CHARACTERISTICS DURING ENFLURANE AND HALOTHANE ANAESTHESIA |
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Authors: | ROYSTON, D. SNOWDON, S. L. |
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Affiliation: | University Department of Anaesthesia, The University of Liverpool, Royal Liverpool Hospital P.O. Box 147, Liverpool L69 3BX |
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Abstract: | The effects of enflurane on certain respiratory characteristicswere compared with those of halothane in 70 patients duringanaesthesia with spontaneous breathing using a specially designedcircuit. The rate of respiration with enflurane (mean 22 b.p.m.)was slower than with halothane (mean 31 b.p.m.; P<0.001)and the tidal volume greater (enflurane mean 240ml, halothane180ml; P<0.05). There was no statistically significant differencein the minute volume of ventilation or end-tidal carbon dioxideconcentration between the two agents. The effects of a narcoticpremedication were observed in 16 patients in the study. Themain effect was to produce slowing of respiratory rate (enfluranemean 16 b.p.m.; halothane 18 b.p.m.). The value of the respiratorypattern compared with the measurement of heart rate and arterialpressure as a clinical guide during anaesthesia is discussed. |
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