细菌性阴道病与宫颈炎关系的初步探讨

目的：探讨细菌性阴道病(BV)与宫颈炎的关系；确定治疗BV能否增加宫颈炎的治愈率。方法：把符合BV和宫颈炎诊断标准的患者随机分为A、B两组，A组使用甲硝唑 多西环素；B组只使用多西环素。两组均治疗1周，于治疗后的2周和4周分别评价两组的疗效。结果：A组的疗效优于B组；进一步分层显示，BV痊愈患者的宫颈炎治愈率显著高于BV未愈者。结论：治疗BV能显著增加宫颈炎的治愈率，提示BV与宫颈炎之间存在着一定的相关性；甲硝唑治疗宫颈炎有效的机制可能与它的非特异的抗菌作用或者尚未了解的特殊性机制有关。

Primary investigation on the association between bacterial vaginosis and cervicitis

Objective:To determine the association between bacterial vaginosis (BV) and cervicitis and to determine whether or not the treatment of BV would result in improvement of cervicitis. Methods:The patients with BV and cervicitis were randomily divided into two groups. The patients in group A were treated with both doxycycline and metronidazole, and the patients in group B only with doxycycline. All subjects received treatment for one week and the efficacy of the treatment was assessed at week two and week four. Results: The treatment was more effective for both BV and cervicitis in group A than in group B. Further analysis showed that the cure rate of cervicitis in BV group was higher than the patients treated only for cervicitis. Conclusion :Successful treatment of BV could increase cure rate of cervicitis. A certain specific association between BV and cervicitis may exist. Nonspecific antibacterial action or an unrecognized specific mechanism of metronidazole may be suggested.