| 加减清营汤对损伤的血管内皮细胞保护作用研究 |
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| 引用本文： | 吴海涛,王敏,江励华,赵凤鸣,吴颢昕,傅雷.加减清营汤对损伤的血管内皮细胞保护作用研究[J].中华中医药学刊,2008,26(12):2671-2672. |
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| 作者姓名： | 吴海涛 王敏 江励华 赵凤鸣 吴颢昕 傅雷 |
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| 作者单位： | 南京中医药大学基础医学院 |
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| 摘 要： | 目的:观察加减清营汤对H2O2损伤的血管内皮细胞活力和NO、t-PA分泌的影响。方法:H2O2损伤ECV304细胞,随机分为正常组、模型组、血清对照组、加减清营汤组,血清药理学方法给药,MTT法观察细胞活力,同时检测NO和t-PA含量。结果:加减清营汤含药血清能明显提高H2O2损伤的ECV304细胞活力和NO、t-PA分泌。结论:加减清营汤对H2O2造成的ECV304细胞损伤具有保护和修复作用。
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| 关 键 词： | 加减清营汤 血栓闭塞性脉管炎 血管内皮细胞 |
Influence of Modified Qingying Decoction on Damaged Vascular Endothelial Cell |
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| WU Hai-tao,WANG Min,JIANG Li-hua,ZHAO Feng-ming,WU Hao-xin,FU Lei.Influence of Modified Qingying Decoction on Damaged Vascular Endothelial Cell[J].Chinese Archives of Traditional Chinese Medicine,2008,26(12):2671-2672. |
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| Authors: | WU Hai-tao WANG Min JIANG Li-hua ZHAO Feng-ming WU Hao-xin FU Lei |
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| Abstract: | Objective:To study the influence of Modified Qingying Decoction on ECV304 cell damaged by H2O2.Methods:The drug-containing serum was obtained from rat administered with Modified Qingying Decoction.After the damaged ECV304 cell by H2O2 was treated with drug-containing serum or control,the drug action was evaluated by the MTT method,the content of nitrogen monoxide(NO) and tissue plasminogen activator(t-PA).Results:Comparing with control group,Modified Qingying Decoction group showed significant increase in cell vigor,the content of NO and t-PA.Conclusion:The "Modified Qingying Decoction could obviously protect ECV304 from injury induced by H2O2. |
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| Keywords: | Modified Qingying Decoction TAO vascular endothelial cell |
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