马来酸曲美布汀治疗肝硬化患者胃电节律紊乱的临床疗效

目的分析肝硬化患者胃电图变化及马来酸曲美布汀治疗胃功能紊乱的有效性。方法95例患者按照肝功能分级分为2组，马来酸曲美布汀治疗前后对比，进行胃电图检查及症状分析。结果治疗后胃电图峰值幅度、胃电主频较治疗前明显改善（P〈0．05），治疗后患者症状明显改善。结论肝硬化患者胃蠕动和胃排空能力下降，予马来酸曲美布汀治疗能改善其胃电生理和临床症状。

Curative effect of trimebutine maleate on gastric dynamic disorder in patients with cirrhosis

Aim To analyze the change of electrogastrogram（EGG） and estimate the efficacy of trimebutine maleate in treatment of gastric dynamic disorder in patients with cirrhosis. Methods 95 patients were divided into two groups by liver function. Patients with gastric dynamic disorder were examined with EGG before and after the treatment of trimebutine maleate and their symptoms were assessed simultaneously. Results There was significant difference between them. EGG examinations before and after meal showed that average frequency was reversed to normal level after treatment with trimebutine maleate. The symptoms of patients were also improved after the treatment （P 〈 0. 05 ）. Conclusion Trimebutine maleate can relieve symptoms and improve the average frequency of EGG in patients of cirrhosis with gastric dynamic disorder.