| 原发性肝细胞癌胞核及核内包涵体的超微结构研究 |
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| 引用本文： | 王文亮 刘健. 原发性肝细胞癌胞核及核内包涵体的超微结构研究[J]. 临床与实验病理学杂志, 1990, 6(3): 153-156 |
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| 作者姓名： | 王文亮 刘健 |
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| 作者单位： | 解放军第四军医大学病解教研室(王文亮)，解放军第四军医大学电镜室(刘健)，解放军第四军医大学电镜室(李学荣) |
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| 摘 要： | 通过光镜和电镜研究了人原发性肝细胞癌胞核及核内包涵体的形态改变、结构、性质和意义。光镜下肝癌胞核普遍增大、核膜增厚、核仁明显。电镜下胞核明显畸形,核内可见各种形态的假包涵体,检出率为73%,还可以见到其他包涵体。越是分化差的肝癌,核的改变越明显。核的改变情况可作为衡量肝癌分化程度的指标之一。
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| 关 键 词： | 肝细胞癌 核内包涵体 超微结构 |
Ultrastructural Study of Cellular Nuclei and Nuclear Inclusions in Primary Hepatocellular Carcinoma |
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| Wang Wenliang et al. Ultrastructural Study of Cellular Nuclei and Nuclear Inclusions in Primary Hepatocellular Carcinoma[J]. Chinese Journal of Clinical and Experimental Pathology, 1990, 6(3): 153-156 |
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| Authors: | Wang Wenliang et al |
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| Abstract: | The specimens of 55 cases of primary hepatocellular carcinoma were observed with light and electron microscope respectively. Under light microscope, the cellular nuclei of hepatoma were enlarged, and the nuclear membranes thickened. The nucleoli were noticeable. Under electron microscope, the shape of nuclei was quite irregular.Various pseudoinclusions were found in cellular nuclei of the most hepatomas, and the rate was 73%. All pseudoinclusions were surrounded by nuclear membrane. They contained normal or degenerative mitochondria, endoplasmic reticulum, lipid vacuoles and other organelles. The more poor-differentiated hepatoma the more marked changes of cellular nuclei. Therefore, the changed status of cellular nuclei may be used as a criterion for measuring difference degree of hepatoma. |
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| Keywords: | hepatocellular carcinoma nuclear inclusion ultrastructure |
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